AT4G29810.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.548 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : MAP kinase kinase 2 | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a MAP kinase kinase 2 that regulates MPK6 and MPK4 in response to cold and salt stresses. Co-expression with MEKK1 in protoplasts activated MKK2 activity, suggesting that MEKK1 may be a regulator of MKK2. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MAP kinase kinase 2 (MKK2); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: cold acclimation, MAPKKK cascade, response to salt stress, response to cold, defense response, incompatible interaction; LOCATED IN: plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: MAP kinase/ ERK kinase 1 (TAIR:AT4G26070.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:-:14593479..14595241 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 37267.90 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.89 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.11 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 338 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MKKGGFSNNL KLAIPVAGEQ SITKFLRKGF GSLCRTQSGT FKDGDLRVNK DGVRIISQLE PEVLSPIKPA DDQLSLSDLD MVKVIGKGSS GVVQLVQHKW 101: TGQFFALKVI QLNIDEAIRK AIAQELKINQ SSQCPNLVTS YQSFYDNGAI SLILEYMDGG SLADFLKSVK AIPDSYLSAI FRQVLQGLIY LHHDRHIIHR 201: DLKPSNLLIN HRGEVKITDF GVSTVMTNTA GLANTFVGTY NYMSPERIVG NKYGNKSDIW SLGLVVLECA TGKFPYAPPN QEETWTSVFE LMEAIVDQPP 301: PALPSGNFSP ELSSFISTCL QKDPNSRSSA KELMVCFI |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)