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AT4G26070.3
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.901
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MAP kinase/ ERK kinase 1
Curator
Summary (TAIR10)
Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4, in response to stress. Gets phosphorylated by MEKK1 in response to wounding.
Computational
Description (TAIR10)
MAP kinase/ ERK kinase 1 (MEK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: MAP kinase kinase 2 (TAIR:AT4G29810.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G26070-MONOMERBioCyc:ARA:GQT-1678-MONOMERBioCyc:ARA:GQT-1679-MONOMERBioGrid:14000
BRENDA:2.7.12.2EC:2.7.12.2eggNOG:ENOG410XQ5AeggNOG:KOG0581
EMBL:AB004796EMBL:AF000977EMBL:AL049483EMBL:AL161564
EMBL:AY050774EMBL:AY087065EMBL:BT001935EMBL:CP002687
EnsemblPlants:AT4G26070EnsemblPlants:AT4G26070.2EnsemblPlants:AT4G26070.3entrez:828713
GeneID:828713Genevisible:Q94A06GO:GO:0000165GO:GO:0000187
GO:GO:0002237GO:GO:0004674GO:GO:0004708GO:GO:0005524
GO:GO:0005737GO:GO:0007346GO:GO:0009414GO:GO:0009611
GO:GO:0009814GO:GO:0031098GO:GO:0042542GO:GO:0042742
hmmpanther:PTHR24361hmmpanther:PTHR24361:SF385HOGENOM:HOG000234206InParanoid:Q94A06
IntAct:Q94A06InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009
InterPro:IPR017441iPTMnet:Q94A06KEGG:ath:AT4G26070OMA:YIHHERR
PaxDb:Q94A06Pfam:PF00069Pfam:Q94A06Pfscan:PS50011
PhylomeDB:Q94A06PIR:T04262PRIDE:Q94A06PRO:PR:Q94A06
PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q94A06
Proteomes:UP000006548Reactome:R-ATH-110056Reactome:R-ATH-112411Reactome:R-ATH-2559580
Reactome:R-ATH-445144Reactome:R-ATH-450302Reactome:R-ATH-450321Reactome:R-ATH-5674135
Reactome:R-ATH-5674499RefSeq:NP_194337.1RefSeq:NP_849446.1RefSeq:NP_974619.1
scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:Q94A06
STRING:3702.AT4G26070.2SUPFAM:SSF56112TAIR:AT4G26070tair10-symbols:ATMEK1
tair10-symbols:MEK1tair10-symbols:MKK1tair10-symbols:NMAPKKUniGene:At.21332
UniGene:At.223UniProt:Q94A06
Coordinates (TAIR10) chr4:+:13217797..13219695
Molecular Weight (calculated) 39212.30 Da
IEP (calculated) 7.66
GRAVY (calculated) -0.16
Length 354 amino acids
Sequence (TAIR10)
(BLAST)
001: MNRGSLCPNP ICLPPLEQSI SKFLTQSGTF KDGDLRVNKD GIQTVSLSEP GAPPPIEPLD NQLSLADLEV IKVIGKGSSG NVQLVKHKLT QQFFALKVIQ
101: LNTEESTCRA ISQELRINLS SQCPYLVSCY QSFYHNGLVS IILEFMDGGS LADLLKKVGK VPENMLSAIC KRVLRGLCYI HHERRIIHRD LKPSNLLINH
201: RGEVKITDFG VSKILTSTSS LANSFVGTYP YMSPERISGS LYSNKSDIWS LGLVLLECAT GKFPYTPPEH KKGWSSVYEL VDAIVENPPP CAPSNLFSPE
301: FCSFISQCVQ KDPRDRKSAK ELLEHKFVKM FEDSDTNLSA YFTDAGSLIP PLAN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)