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AT4G24190.2
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Predictors External Curations
SwissProt : endoplasmic reticulum 16381842
TAIR : plastid 15028209
TAIR : vacuole 15539469
TAIR : nucleus 14617066
TAIR : plastid 18431481
TAIR : plasma membrane 17644812
TAIR : mitochondrion 14671022
TAIR : endoplasmic reticulum 11867518
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Chaperone protein htpG family protein
Curator
Summary (TAIR10)
encodes an ortholog of GRP94, an ER-resident HSP90-like protein and is involved in regulation of meristem size and organization. Single and double mutant analyses suggest that SHD may be required for the correct folding and/or complex formation of CLV proteins. Lines carrying recessive mutations in this locus exhibits expanded shoot meristems, disorganized root meristems, and defective pollen tube elongation. Transcript is detected in all tissues examined and is not induced by heat. Endoplasmin supports the protein secretory pathway and has a role in proliferating tissues.
Computational
Description (TAIR10)
SHEPHERD (SHD); FUNCTIONS IN: unfolded protein binding, ATP binding; INVOLVED IN: in 8 processes; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Molecular chaperone, heat shock protein, endoplasmin (InterPro:IPR015566), ATPase-like, ATP-binding domain (InterPro:IPR003594), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: heat shock protein 90.1 (TAIR:AT5G52640.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0326eggNOG:KOG0020EMBL:CP002687EnsemblPlants:AT4G24190
EnsemblPlants:AT4G24190.2entrez:828520ExpressionAtlas:F4JQ55Gene3D:3.30.565.10
GeneID:828520GO:GO:0005524GO:GO:0006457GO:GO:0006950
Gramene:AT4G24190.2HAMAP:MF_00505hmmpanther:PTHR11528hmmpanther:PTHR11528:SF45
InterPro:IPR001404InterPro:IPR003594InterPro:IPR019805InterPro:IPR020568
InterPro:IPR020575ncoils:CoilPANTHER:PTHR11528PaxDb:F4JQ55
Pfam:PF00183Pfam:PF02518PIRSF:PIRSF002583PRIDE:F4JQ55
PRINTS:PR00775PROSITE:PS00298ProteinModelPortal:F4JQ55Proteomes:UP000006548
RefSeq:NP_974606.1scanprosite:PS00298SMART:SM00387SMR:F4JQ55
STRING:3702.AT4G24190.1SUPFAM:0043579SUPFAM:SSF54211SUPFAM:SSF55874
TAIR:AT4G24190tair10-symbols:AtHsp90-7tair10-symbols:AtHsp90.7tair10-symbols:SHD
UniGene:At.24111UniProt:F4JQ55
Coordinates (TAIR10) chr4:-:12551902..12555851
Molecular Weight (calculated) 94153.70 Da
IEP (calculated) 4.64
GRAVY (calculated) -0.70
Length 823 amino acids
Sequence (TAIR10)
(BLAST)
001: MRKRTLVSVL FLFSLLFLLP DQGTKLHANA EESSDDVTDP PKVEEKIGGH GGLSTDSDVV HRESESMSKK TLRSNAEKFE FQAEVSRLMD IIINSLYSNK
101: DIFLRELISN ASDALDKIRF LALTDKDVLG EGDTAKLEIQ IKLDKAKKIL SIRDRGIGMT KEDLIKNLGT IAKSGTSAFV EKMQSSGDLN LIGQFGVGFY
201: SAYLVADYIE VISKHNDDSQ YVWESKANGK FAVSEDTWNE PLGRGTEIRL HLRDEAGEYL EESKLKELVK RYSEFINFPI SLWASKEVET EVPVEEDESA
301: DEETETTSTE EEKEEDAEEE DGEKKQKTKK VKETVYEWEL LNDVKAIWLR SPKEVTEEEY TKFYHSLSKD FTDEKPMAWS HFNAEGDVEF KAVLYVPPKA
401: PHDLYESYYN SNKANLKLYV RRVFISDEFD ELLPKYLSFL KGLVDSDTLP LNVSREMLQQ HSSLKTIKKK LIRKALDMIR KLAEEDPDEI HDDEKKDVEK
501: SGENDEKKGQ YTKFWNEFGK SVKLGIIEDA ANRNRLAKLL RFETTKSDGK LTSLDQYIKR MKKSQKDIFY ITGSSKEQLE KSPFLERLIK KGYEVIFFTD
601: PVDEYLMQYL MDYEDKKFQN VSKEGLKVGK DSKDKELKEA FKELTKWWKG NLASENVDDV KISNRLADTP CVVVTSKFGW SANMERIMQS QTLSDANKQA
701: YMRGKRVLEI NPRHPIIKEL KDRIASDPED ESVKETAQLM YQTALIESGF ILTDPKDFAA RIYNSVKSGL NISPDAVADE EIEAAEEPET SEATETKSDD
801: LAGGLNIEAE PVEQQEENTK DEL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)