AT4G21980.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.500 vacuole 0.500 ASURE: cytosol,vacuole What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Ubiquitin-like superfamily protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes APG8, a component of autophagy conjugation pathway. Delivered to the lumens of vacuole under nitrogen-starvation condition. Highest expression in flowers. mRNA abundance increased during dark-induced carbon starvation. Predominantly cytoplasmic with or without N starvation. Upon concanamycin A the protein accumulates in the central vacuole as punctuate structures that resemble autophagic bodies. This localization is more abundant upon N starvation. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
AUTOPHAGY 8A (APG8A); FUNCTIONS IN: APG8-specific protease activity, APG8 activating enzyme activity, Atg8 ligase activity; INVOLVED IN: autophagy; LOCATED IN: vacuolar lumen, autophagic vacuole, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241); BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT4G04620.2); Has 1531 Blast hits to 1529 proteins in 269 species: Archae - 0; Bacteria - 0; Metazoa - 726; Fungi - 172; Plants - 305; Viruses - 3; Other Eukaryotes - 325 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:+:11655868..11656809 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 15405.70 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.33 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.12 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 137 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MIFACLKFAE TNRIAMAKSS FKISNPLEAR MSESSRIREK YPDRIPVIVE KAGQSDVPDI DKKKYLVPAD LTVGQFVYVV RKRIKLGAEK AIFVFVKNTL 101: PPTAALMSAI YEEHKDEDGF LYMTYSGENT FGSLTVA |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)