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AT4G17380.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : MUTS-like protein 4
Curator
Summary (TAIR10)
Encodes the Arabidopsis homolog of MSH4, a meiosis-specific member of the MutS-homolog family of genes. It is expressed only in floral tissues and only during early meiotic prophase I, preceding the synapsis of homologous chromosomes. It is involved in the early steps of recombination.
Computational
Description (TAIR10)
MUTS-like protein 4 (MSH4); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, synapsis, meiotic prophase I; LOCATED IN: condensed nuclear chromosome; EXPRESSED IN: flower, sporocyte; EXPRESSED DURING: petal differentiation and expansion stage, IL.00 inflorescence just visible; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS, core (InterPro:IPR007696); BEST Arabidopsis thaliana protein match is: MUTS homolog 2 (TAIR:AT3G18524.1); Has 13303 Blast hits to 13154 proteins in 2712 species: Archae - 169; Bacteria - 9120; Metazoa - 661; Fungi - 837; Plants - 451; Viruses - 3; Other Eukaryotes - 2062 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0249eggNOG:KOG0220EMBL:AL161546EMBL:AY646927
EMBL:CP002687EMBL:Z97343EnsemblPlants:AT4G17380EnsemblPlants:AT4G17380.1
entrez:827450Gene3D:3.40.50.300GeneID:827450Genevisible:F4JP48
GO:GO:0000794GO:GO:0000795GO:GO:0005524GO:GO:0007129
GO:GO:0009506GO:GO:0010777GO:GO:0030983GO:GO:0043073
GO:GO:0045143Gramene:AT4G17380.1hmmpanther:PTHR11361hmmpanther:PTHR11361:SF21
HOGENOM:HOG000290656InParanoid:F4JP48IntAct:F4JP48InterPro:IPR000432
InterPro:IPR007696InterPro:IPR007861InterPro:IPR011184InterPro:IPR027417
KEGG:ath:AT4G17380KO:K08740OMA:WTPQMGYPaxDb:F4JP48
Pfam:F4JP48Pfam:PF00488Pfam:PF05190Pfam:PF05192
PIR:B71443PIRSF:PIRSF005813PRIDE:F4JP48PRO:PR:F4JP48
ProteinModelPortal:F4JP48Proteomes:UP000006548RefSeq:NP_193469.2SMART:SM00533
SMART:SM00534SMR:F4JP48STRING:3702.AT4G17380.1SUPFAM:SSF48334
SUPFAM:SSF52540TAIR:AT4G17380tair10-symbols:ATMSH4tair10-symbols:MSH4
UniGene:At.24376UniGene:At.71316UniProt:F4JP48
Coordinates (TAIR10) chr4:+:9708742..9714068
Molecular Weight (calculated) 89019.70 Da
IEP (calculated) 7.75
GRAVY (calculated) -0.07
Length 792 amino acids
Sequence (TAIR10)
(BLAST)
001: MEDDGGERSS FVAGLIENRA KEVGMAAFDL RSASLHLSQY IETSSSYQNT KTLLRFYDPS VIIVPPNKLA ADGMVGVSEL VDRCYSTVRK VVFARGCFDD
101: TKGAVLIQNL AAEEPLALGL DTYYKQHYLS LAAAAATIKW IEAEKGVIVT NHSLTVTFNG SFDHMNIDAT SVENLELIDP FHNALLGTSN KKRSLFQMFK
201: TTKTAGGTRL LRANLLQPLK DIETINTRLD CLDELMSNEQ LFFGLSQVLR KFPKETDRVL CHFCFKPKKV TEAVIGFENT RKSQNMISSI ILLKTALDAL
301: PILAKVLKDA KCFLLANVYK SVCENDRYAS IRKKIGEVID DDVLHARVPF VARTQQCFAL KAGIDGFLDI ARRTFCDTSE AIHNLASKYR EEFNLPNLKL
401: PFNNRQGFFF RIPQKEVQGK LPNKFTQVVK HGKNIHCSSL ELASLNVRNK SAAGECFIRT ETCLEALMDA IREDISALTL LAEVLCLLDM IVNSFAHTIS
501: TKPVDRYSRP ELTDSGPLAI DAGRHPILES IHNDFVSNSI FMSEATNMLV VMGPNMSGKS TYLQQVCLVV ILAQIGCYVP ARFATIRVVD RIFTRMGTMD
601: NLESNSSTFM TEMRETAFIM QNVTNRSLIV MDELGRATSS SDGLAMAWSC CEYLLSLKAY TVFATHMDSL AELATIYPNV KVLHFYVDIR DNRLDFKFQL
701: RDGTLHVPHY GLLLAEVAGL PSTVIDTARI ITKRITDKEN KRIELNCGKH HEIHRIYRVA QRLICLKYSR QTEDSIRQAL QNLNESFTEE RL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)