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AT4G16566.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : histidine triad nucleotide-binding 4
Curator
Summary (TAIR10)
Encodes a protein that has an unexpected bifunctional capability in vitro. The purified enzyme has adenylylsulfate sulfohydrolase activity (E.C. 3.6.2.1) and ADP-sulfurylase activity (E.C. 2.7.7.5). The latter is activated at low pH. The enzyme can exert it phosphorylase activity on a range of related substrates in vitro, but it acts best with APS (adenosine 5'-phsophosulfate). This protein appears to function as a homodimer.
Computational
Description (TAIR10)
histidine triad nucleotide-binding 4 (HINT4); FUNCTIONS IN: adenylylsulfatase activity, sulfate adenylyltransferase (ADP) activity, nucleotide binding; INVOLVED IN: sulfur metabolic process, purine ribonucleotide metabolic process, nucleotide metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Histidine triad-like motif (InterPro:IPR011146), Histidine triad (HIT) protein (InterPro:IPR001310), Histidine triad motif (InterPro:IPR011151); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BRENDA:2.7.7.5eggNOG:ENOG4111MVJeggNOG:KOG4359EMBL:AK175206
EMBL:AK176221EMBL:BT004792EMBL:CP002687EnsemblPlants:AT4G16566
EnsemblPlants:AT4G16566.1entrez:827357Gene3D:3.30.428.10GeneID:827357
GO:GO:0004780GO:GO:0005777GO:GO:0006790GO:GO:0009150
GO:GO:0047627Gramene:AT4G16566.1hmmpanther:PTHR12486InterPro:IPR001310
InterPro:IPR011146KEGG:ath:AT4G16566OMA:NDLQRRDPfam:PF11969
Pfscan:PS51084PRINTS:PR00332PROSITE:PS51084Proteomes:UP000006548
RefSeq:NP_567507.1SMR:Q84VV6STRING:3702.AT4G16566.1SUPFAM:SSF54197
TAIR:AT4G16566tair10-symbols:HINT4UniGene:At.22235UniProt:Q84VV6
Coordinates (TAIR10) chr4:-:9334873..9335884
Molecular Weight (calculated) 16798.50 Da
IEP (calculated) 9.22
GRAVY (calculated) -0.24
Length 146 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGVNQACIF CEIVRNPTTT RLLHTDEKVI AFQDIKPAAQ RHYLVIPKEH IPTVNDLQRR DEDYSLVRHM LSVGQQLLQK DAPQSIHRFG FHQPPFNSVD
101: HLHLHCFALP YVPRWKAIKY KSLGPLGGFI EAETLLEKIR PLLSKV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)