AT4G15530.4
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:cytosol 0.500 plastid 0.500 ASURE: cytosol,plastid What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : pyruvate orthophosphate dikinase | ||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a dual-targeted protein believed to act as a pyruvate, orthophosphate dikinase. These enzymes are normally associated with C4 photosynthesis which does not occur in Arabidopsis. However, PPDK may play a role in remobilizing nitrogen during leaf senescence in Arabidopsis. The product of the long transcript (.1 gene model) was shown to be targeted to the chloroplast, whereas the shorter transcript (no targeting sequence) accumulates in the cytosol. The two proteins were also found to be expressed in slightly different tissues. | ||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
pyruvate orthophosphate dikinase (PPDK); FUNCTIONS IN: kinase activity, pyruvate, phosphate dikinase activity; INVOLVED IN: phosphorylation, response to absence of light; LOCATED IN: cytosol, nucleus, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: PEP-utilising enzyme, mobile domain (InterPro:IPR008279), ATP-grasp fold, subdomain 1 (InterPro:IPR013815), Pyruvate, phosphate dikinase (InterPro:IPR010121), Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Pyruvate phosphate dikinase, PEP/pyruvate-binding (InterPro:IPR002192), PEP-utilising enzyme, mobile region, conserved site (InterPro:IPR018274), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), PEP-utilising enzyme (InterPro:IPR000121); Has 15226 Blast hits to 15137 proteins in 2575 species: Archae - 291; Bacteria - 9909; Metazoa - 12; Fungi - 19; Plants - 160; Viruses - 0; Other Eukaryotes - 4835 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr4:-:8864828..8870727 | ||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 104211.00 Da | ||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 6.07 | ||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.17 | ||||||||||||||||||||||||||||||||||||||||||||
Length | 956 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MTSMIVKTTP ELFKGNGVFR TDHLGENRMV SRSNRLGDGS NRFPRTGTIH CQRLSIAKTG LHRETKARAI LSPVSDPAAS IAQKRVFTFG KGRSEGNKGM 101: KSLLGGKGAN LAEMASIGLS VPPGLTISTE ACQQYQIAGK KLPEGLWEEI LEGLSFIERD IGASLADPSK PLLLSVRSGA AISMPGMMDT VLNLGLNDQV 201: VVGLAAKSGE RFAYDSFRRF LDMFGDVVMG IPHAKFEEKL ERMKERKGVK NDTDLSAADL KELVEQYKSV YLEAKGQEFP SDPKKQLELA IEAVFDSWDS 301: PRANKYRSIN QITGLKGTAV NIQCMVFGNM GDTSGTGVLF TRNPSTGEKK LYGEFLVNAQ GEDVVAGIRT PEDLDTMKRF MPEAYAELVE NCNILERHYK 401: DMMDIEFTVQ EERLWMLQCR AGKRTGKGAV KIAVDMVGEG LVEKSSAIKM VEPQHLDQLL HPQFHDPSGY REKVVAKGLP ASPGAAVGQV VFTAEEAEAW 501: HSQGKTVILV RTETSPDDVG GMHAAEGILT ARGGMTSHAA VVARGWGKCC IAGCSEIRVD ENHKVLLIGD LTINEGEWIS MNGSTGEVIL GKQALAPPAL 601: SPDLETFMSW ADAIRRLKVM ANADTPEDAI AARKNGAQGI GLCRTEHMFF GADRIKAVRK MIMAVTTEQR KASLDILLPY QRSDFEGIFR AMDGLPVTIR 701: LLDPPLHEFL PEGDLDNIVH ELAEETGVKE DEVLSRIEKL SEVNPMLGFR GCRLGISYPE LTEMQARAIF EAAASMQDQG VTVIPEIMVP LVGTPQELGH 801: QVDVIRKVAK KVFAEKGHTV SYKVGTMIEI PRAALIADEI AKEAEFFSFG TNDLTQMTFG YSRDDVGKFL PIYLAKGILQ HDPFEVLDQQ GVGQLIKMAT 901: EKGRAARPSL KVGICGEHGG DPSSVGFFAE AGLDYVSCSP FRVPIARLAA AQVVVA |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)