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AT4G13940.4
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : S-adenosyl-L-homocysteine hydrolase
Curator
Summary (TAIR10)
Encodes a S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing.
Computational
Description (TAIR10)
HOMOLOGY-DEPENDENT GENE SILENCING 1 (HOG1); FUNCTIONS IN: adenosylhomocysteinase activity; INVOLVED IN: methylation-dependent chromatin silencing, one-carbon metabolic process, posttranscriptional gene silencing, embryo development ending in seed dormancy; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 34 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosyl-L-homocysteine hydrolase (InterPro:IPR000043), S-adenosyl-L-homocysteine hydrolase, conserved site (InterPro:IPR020082), NAD(P)-binding domain (InterPro:IPR016040), S-adenosyl-L-homocysteine hydrolase, NAD binding (InterPro:IPR015878); BEST Arabidopsis thaliana protein match is: S-adenosyl-l-homocysteine (SAH) hydrolase 2 (TAIR:AT3G23810.1); Has 6788 Blast hits to 6786 proteins in 1444 species: Archae - 223; Bacteria - 2243; Metazoa - 514; Fungi - 135; Plants - 203; Viruses - 0; Other Eukaryotes - 3470 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0499eggNOG:KOG1370EMBL:CP002687EnsemblPlants:AT4G13940
EnsemblPlants:AT4G13940.4entrez:827028ExpressionAtlas:A8MQP1GeneID:827028
GO:GO:0004013GO:GO:0006730Gramene:AT4G13940.4gramene_pathway:3.3.1.1
gramene_pathway:PWY-5041gramene_plant_reactome:1119501gramene_plant_reactome:6876108hmmpanther:PTHR23420
HOGENOM:HOG000227986InterPro:IPR000043InterPro:IPR015878InterPro:IPR016040
InterPro:IPR020082KEGG:00270+3.3.1.1PANTHER:PTHR23420PaxDb:A8MQP1
Pfam:PF00670Pfam:PF05221PRIDE:A8MQP1ProMEX:A8MQP1
PROSITE:PS00738PROSITE:PS00739ProteinModelPortal:A8MQP1Proteomes:UP000006548
RefSeq:NP_001078387.1scanprosite:PS00738scanprosite:PS00739SMART:SM00996
SMART:SM00997SMR:A8MQP1STRING:3702.AT4G13940.1SUPFAM:SSF51735
SUPFAM:SSF52283TAIR:AT4G13940tair10-symbols:HOG1tair10-symbols:SAHH1
UniGene:At.24056UniGene:At.24845UniGene:At.71956UniGene:At.74987
UniGene:At.74988unipathway:UPA00314UniProt:A8MQP1
Coordinates (TAIR10) chr4:+:8054931..8056763
Molecular Weight (calculated) 35533.80 Da
IEP (calculated) 4.80
GRAVY (calculated) -0.04
Length 325 amino acids
Sequence (TAIR10)
(BLAST)
001: MALLVEKTSS GREYKVKDMS QADFGRLELE LAEVEMPGLM ACRTEFGPSQ PFKGARITGS LHMTIQTAVL IETLTALGAE VRWCSCNIFS TQDHAAAAIA
101: RDSAAVFAWK GETLQEYWWC TERALDWGPG GGPDLIVDDG GDATLLIHEG VKAEEIFEKT GQVPDPTSTD NPEFQIVLSI IKEGLQVDPK KYHKMKERLV
201: GVSEETTTGV KRLYQMQQNG TLLFPAINVN DSVTKSKFDN LYGCRHSLPD GLMRATDVMI AGKVAVICGY GDVGKGCAAA MKTAGARVIV TEIDPICALQ
301: ALMEGLQVRI YLWFCVGLWW ESGTV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)