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AT4G13940.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.997
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : S-adenosyl-L-homocysteine hydrolase
Curator
Summary (TAIR10)
Encodes a S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing.
Computational
Description (TAIR10)
HOMOLOGY-DEPENDENT GENE SILENCING 1 (HOG1); FUNCTIONS IN: adenosylhomocysteinase activity, copper ion binding; INVOLVED IN: methylation-dependent chromatin silencing, one-carbon metabolic process, posttranscriptional gene silencing, embryo development ending in seed dormancy; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosyl-L-homocysteine hydrolase (InterPro:IPR000043), S-adenosyl-L-homocysteine hydrolase, conserved site (InterPro:IPR020082), S-adenosyl-L-homocysteine hydrolase, NAD binding (InterPro:IPR015878); BEST Arabidopsis thaliana protein match is: S-adenosyl-l-homocysteine (SAH) hydrolase 2 (TAIR:AT3G23810.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
EC:3.3.1.1EMBL:CP002687EnsemblPlants:AT4G13940EnsemblPlants:AT4G13940.3
entrez:827028ExpressionAtlas:F4JTV4Gene3D:3.40.50.720GeneID:827028
GO:GO:0004013GO:GO:0006730Gramene:AT4G13940.3gramene_pathway:3.3.1.1
gramene_pathway:PWY-5041gramene_plant_reactome:1119501gramene_plant_reactome:6876108hmmpanther:PTHR23420
InterPro:IPR000043InterPro:IPR015878InterPro:IPR016040InterPro:IPR020082
KEGG:00270+3.3.1.1PANTHER:PTHR23420Pfam:PF00670Pfam:PF05221
PIRSF:PIRSF001109PRIDE:F4JTV4PROSITE:PS00738PROSITE:PS00739
ProteinModelPortal:F4JTV4Proteomes:UP000006548RefSeq:NP_001031628.1scanprosite:PS00738
scanprosite:PS00739SMART:SM00996SMART:SM00997SMR:F4JTV4
SUPFAM:SSF51735SUPFAM:SSF52283TAIR:AT4G13940tair10-symbols:HOG1
tair10-symbols:SAHH1TIGRfam:TIGR00936TIGRFAMs:TIGR00936UniGene:At.24056
UniGene:At.24845UniGene:At.71956UniGene:At.74987UniGene:At.74988
UniPathway:UPA00314UniProt:F4JTV4
Coordinates (TAIR10) chr4:+:8054931..8056676
Molecular Weight (calculated) 48409.90 Da
IEP (calculated) 6.84
GRAVY (calculated) -0.12
Length 440 amino acids
Sequence (TAIR10)
(BLAST)
001: MALLVEKTSS GREYKVKDMS QADFGRLELE LAEVEMPGLM ACRTEFGPSQ PFKGARITGS LHMTIQTAVL IETLTALGAE VRWCSCNIFS TQDHAAAAIA
101: RDSAGVKAEE IFEKTGQVPD PTSTDNPEFQ IVLSIIKEGL QVDPKKYHKM KERLVGVSEE TTTGVKRLYQ MQQNGTLLFP AINVNDSVTK SKFDNLYGCR
201: HSLPDGLMRA TDVMIAGKVA VICGYGDVGK GCAAAMKTAG ARVIVTEIDP ICALQALMEG LQVLTLEDVV SEADIFVTTT GNKDIIMVDH MRKMKNNAIV
301: CNIGHFDNEI DMLGLETYPG VKRITIKPQT DRWVFPETKA GIIVLAEGRL MNLGCATGHP SFVMSCSFTN QVIAQLELWN EKASGKYEKK VYVLPKHLDE
401: KVALLHLGKL GARLTKLSKD QSDYVSIPIE GPYKPPHYRY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)