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AT4G08470.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.997
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MAPK/ERK kinase kinase 3
Curator
Summary (TAIR10)
Encodes a member of the A1 subgroup of the MEKK (MAPK/ERK kinase kinase) family. MEKK is another name for Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK or MAP3K). This subgroup has four members: At4g08500 (MEKK1, also known as ARAKIN, MAP3Kb1, MAPKKK8), At4g08480 (MEKK2, also known as MAP3Kb4, MAPKKK9), At4g08470 (MEKK3, also known as MAP3Kb3, MAPKKK10) and At4g12020 (MEKK4, also known as MAP3Kb5, MAPKKK11, WRKY19). Nomenclatures for mitogen-activated protein kinases are described in Trends in Plant Science 2002, 7(7):301.
Computational
Description (TAIR10)
MAPK/ERK kinase kinase 3 (MEKK3); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: MAPK/ERK kinase kinase 1 (TAIR:AT4G08500.1); Has 127289 Blast hits to 125542 proteins in 4465 species: Archae - 126; Bacteria - 13573; Metazoa - 48244; Fungi - 12466; Plants - 31976; Viruses - 540; Other Eukaryotes - 20364 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G08470-MONOMEReggNOG:ENOG410XQGSeggNOG:KOG0198EMBL:AL161511
EMBL:BT021102EMBL:CP002687EnsemblPlants:AT4G08470EnsemblPlants:AT4G08470.1
entrez:826406GeneID:826406GO:GO:0004672GO:GO:0005524
Gramene:AT4G08470.1hmmpanther:PTHR24361hmmpanther:PTHR24361:SF318InterPro:IPR000719
InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441KEGG:ath:AT4G08470
Pfam:PF00069Pfscan:PS50011PhylomeDB:Q9M0T3PIR:D85084
PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011Proteomes:UP000006548
RefSeq:NP_192587.1scanprosite:PS00107scanprosite:PS00108SMART:SM00220
SMR:Q9M0T3STRING:3702.AT4G08470.1SUPFAM:SSF56112TAIR:AT4G08470
tair10-symbols:MAPKKK10tair10-symbols:MEKK3UniGene:At.28670UniProt:Q9M0T3
Coordinates (TAIR10) chr4:-:5384030..5387038
Molecular Weight (calculated) 62311.10 Da
IEP (calculated) 5.60
GRAVY (calculated) -0.29
Length 560 amino acids
Sequence (TAIR10)
(BLAST)
001: MDVTAIFAGD ILVQSREYLI PNDVVDVDGG IKAVRPPIIQ PPPGRKLPLI DFPGSSWDFL TYFAPSKTVK RQSSSSSDNT SDKEEVETEE TRGMFVQLGD
101: TAHEACPFAT NEADSSSTVS IISPSYASRG SIVPSWLKRK FLGRVSLGFV YEGSSGSSVG SESTCSLMTP SLEFPDRISF RKKDFSEKGP SRHVWEKRKL
201: TRAKLIENFC NPEDIEPVTS WLKGQLLGEE SFASVYEAIS DSSVGSESTC SLMTPSMEFP DRISFRKRDF SEEGPSGRVK EKRKLMRNKL IENFRKPEDI
301: TSWLKGQLLG RGSYASVYEA ISEDGDFFAV KEVSLLDKGI QAQECIQQLE GEIALLSQLQ HQNIVRYRGT AKDVSKLYIF LELVTQGSVQ KLYERYQLSY
401: TVVSLYTRQI LAGLNYLHDK GFVHRDIKCA NMLVDANGTV KLADFGLAEA SKFNDIMSCK GTLFWMAPEV INRKDSDGNG SPADIWSLGC TVLEMCTGQI
501: PYSDLKPIQA AFKIGRGTLP DVPDTLSLDA RHFILTCLKV NPEERPTAAE LLHHPFVINL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)