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AT4G02460.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : DNA mismatch repair protein, putative
Curator
Summary (TAIR10)
Encodes a protein similar to PMS1 in yeast, a member of the family of eukaryotic MutL homologs. The protein appears to play a role in DNA mismatch repair and in the suppression of somatic homeologous recombination.
Computational
Description (TAIR10)
POSTMEIOTIC SEGREGATION 1 (PMS1); FUNCTIONS IN: mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, fruit development, seed development, DNA recombination, pollen development; LOCATED IN: nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair, conserved site (InterPro:IPR014762), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA mismatch repair protein, C-terminal (InterPro:IPR013507), MutL, C-terminal, dimerisation (InterPro:IPR014790), DNA mismatch repair protein, N-terminal (InterPro:IPR014763), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA mismatch repair protein (InterPro:IPR002099), Post Meiotic Segregation 2 (InterPro:IPR015434), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721); BEST Arabidopsis thaliana protein match is: MUTL-homologue 1 (TAIR:AT4G09140.1); Has 10471 Blast hits to 7086 proteins in 2377 species: Archae - 138; Bacteria - 7516; Metazoa - 568; Fungi - 666; Plants - 148; Viruses - 0; Other Eukaryotes - 1435 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0323eggNOG:KOG1978EMBL:AF069298EMBL:AK117777
EMBL:AL161494EMBL:AY047228EMBL:CP002687EnsemblPlants:AT4G02460
EnsemblPlants:AT4G02460.1entrez:827997Gene3D:3.30.230.10Gene3D:3.30.565.10
GeneID:827997Genevisible:Q941I6GO:GO:0003697GO:GO:0005524
GO:GO:0005634GO:GO:0006298GO:GO:0006310GO:GO:0009555
GO:GO:0010154GO:GO:0016887GO:GO:0030983GO:GO:0032389
GO:GO:0048316hmmpanther:PTHR10073hmmpanther:PTHR10073:SF12HOGENOM:HOG000165474
InParanoid:Q941I6InterPro:IPR002099InterPro:IPR003594InterPro:IPR013507
InterPro:IPR014721InterPro:IPR014762InterPro:IPR014790InterPro:IPR020568
InterPro:IPR028831iPTMnet:Q941I6KEGG:ath:AT4G02460KO:K10858
OMA:GQFNHGFPANTHER:PTHR10073:SF12PaxDb:Q941I6Pfam:PF01119
Pfam:PF08676Pfam:PF13589Pfam:Q941I6PhylomeDB:Q941I6
PIR:T01304PRIDE:Q941I6PRO:PR:Q941I6PROSITE:PS00058
ProteinModelPortal:Q941I6Proteomes:UP000006548Reactome:R-ATH-5358565RefSeq:NP_567236.1
scanprosite:PS00058SMART:SM00853SMART:SM01340SMR:Q941I6
STRING:3702.AT4G02460.1SUPFAM:0050888SUPFAM:SSF54211SUPFAM:SSF55874
TAIR:AT4G02460tair10-symbols:PMS1TIGRfam:TIGR00585TIGRFAMs:TIGR00585
UniGene:At.26416UniProt:Q941I6
Coordinates (TAIR10) chr4:-:1076306..1080510
Molecular Weight (calculated) 102690.00 Da
IEP (calculated) 6.57
GRAVY (calculated) -0.47
Length 923 amino acids
Sequence (TAIR10)
(BLAST)
001: MQGDSSPSPT TTSSPLIRPI NRNVIHRICS GQVILDLSSA VKELVENSLD AGATSIEINL RDYGEDYFQV IDNGCGISPT NFKVLALKHH TSKLEDFTDL
101: LNLTTYGFRG EALSSLCALG NLTVETRTKN EPVATLLTFD HSGLLTAEKK TARQIGTTVT VRKLFSNLPV RSKEFKRNIR KEYGKLVSLL NAYALIAKGV
201: RFVCSNTTGK NPKSVVLNTQ GRGSLKDNII TVFGISTFTS LQPVSICVSE DCRVEGFLSK PGQGTGRNLA DRQYFFINGR PVDMPKVSKL VNELYKDTSS
301: RKYPVTILDF IVPGGACDLN VTPDKRKVFF SDETSVIGSL REGLNEIYSS SNASYIVNRF EENSEQPDKA GVSSFQKKSN LLSEGIVLDV SSKTRLGEAI
401: EKENPSLREV EIDNSSPMEK FKFEIKACGT KKGEGSLSVH DVTHLDKTPS KGLPQLNVTE KVTDASKDLS SRSSFAQSTL NTFVTMGKRK HENISTILSE
501: TPVLRNQTSS YRVEKSKFEV RALASRCLVE GDQLDDMVIS KEDMTPSERD SELGNRISPG TQADNVERHE REHEKPIRFE EPTSDNTLTK GDVERVSEDN
601: PRCSQPLRSV ATVLDSPAQS TGPKMFSTLE FSFQNLRTRR LERLSRLQST GYVSKCMNTP QPKKCFAAAT LELSQPDDEE RKARALAAAT SELERLFRKE
701: DFRRMQVLGQ FNLGFIIAKL ERDLFIVDQH AADEKFNFEH LARSTVLNQQ PLLQPLNLEL SPEEEVTVLM HMDIIRENGF LLEENPSAPP GKHFRLRAIP
801: YSKNITFGVE DLKDLISTLG DNHGECSVAS SYKTSKTDSI CPSRVRAMLA SRACRSSVMI GDPLRKNEMQ KIVEHLADLE SPWNCPHGRP TMRHLVDLTT
901: LLTLPDDDNV NDDDDDDATI SLA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)