AT4G02070.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : MUTS homolog 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1); Has 29702 Blast hits to 21889 proteins in 2967 species: Archae - 234; Bacteria - 11721; Metazoa - 3243; Fungi - 2118; Plants - 3658; Viruses - 802; Other Eukaryotes - 7926 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr4:+:906079..912930 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 146805.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 6.62 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.50 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 1324 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
0001: MAPSRRQISG RSPLVNQQRQ ITSFFGKSAS SSSSPSPSPS PSLSNKKTPK SNNPNPKSPS PSPSPPKKTP KLNPNPSSNL PARSPSPGPD TPSPVQSKFK 0101: KPLLVIGQTP SPPQSVVITY GDEVVGKQVR VYWPLDKKWY DGSVTFYDKG EGKHVVEYED GEEESLDLGK EKTEWVVGEK SGDRFNRLKR GASALRKVVT 0201: DSDDDVEMGN VEEDKSDGDD SSDEDWGKNV GKEVCESEED DVELVDENEM DEEELVEEKD EETSKVNRVS KTDSRKRKTS EVTKSGGEKK SKTDTGTILK 0301: GFKASVVEPA KKIGQADRVV KGLEDNVLDG DALARFGARD SEKFRFLGVD RRDAKRRRPT DENYDPRTLY LPPDFVKKLT GGQRQWWEFK AKHMDKVVFF 0401: KMGKFYELFE MDAHVGAKEL DIQYMKGEQP HCGFPEKNFS VNIEKLVRKG YRVLVVEQTE TPDQLEQRRK ETGSKDKVVK REVCAVVTKG TLTDGEMLLT 0501: NPDASYLMAL TEGGESLTNP TAEHNFGVCL VDVATQKIIL GQFKDDQDCS ALSCLLSEMR PVEIIKPAKV LSYATERTIV RQTRNPLVNN LVPLSEFWDS 0601: EKTIYEVGII YKRINCQPSS AYSSEGKILG DGSSFLPKML SELATEDKNG SLALSALGGA IYYLRQAFLD ESLLRFAKFE SLPYCDFSNV NEKQHMVLDA 0701: AALENLEIFE NSRNGGYSGT LYAQLNQCIT ASGKRLLKTW LARPLYNTEL IKERQDAVAI LRGENLPYSL EFRKSLSRLP DMERLIARMF SSIEASGRNG 0801: DKVVLYEDTA KKQVQEFIST LRGCETMAEA CSSLRAILKH DTSRRLLHLL TPGQSLPNIS SSIKYFKDAF DWVEAHNSGR VIPHEGADEE YDCACKTVEE 0901: FESSLKKHLK EQRKLLGDAS INYVTVGKDE YLLEVPESLS GSVPHDYELC SSKKGVSRYW TPTIKKLLKE LSQAKSEKES ALKSISQRLI GRFCEHQEKW 1001: RQLVSATAEL DVLISLAFAS DSYEGVRCRP VISGSTSDGV PHLSATGLGH PVLRGDSLGR GSFVPNNVKI GGAEKASFIL LTGPNMGGKS TLLRQVCLAV 1101: ILAQIGADVP AETFEVSPVD KICVRMGAKD HIMAGQSTFL TELSETAVML TSATRNSLVV LDELGRGTAT SDGQAIAESV LEHFIEKVQC RGFFSTHYHR 1201: LSVDYQTNPK VSLCHMACQI GEGIGGVEEV TFLYRLTPGA CPKSYGVNVA RLAGLPDYVL QRAVIKSQEF EALYGKNHRK TDHKLAAMIK QIISSVASDS 1301: DYSASKDSLC ELHSMANTFL RLTN |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)