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AT3G59970.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : methylenetetrahydrofolate reductase 1
Curator
Summary (TAIR10)
methylenetetrahydrofolate reductase MTHFR1 mRNA, complete
Computational
Description (TAIR10)
methylenetetrahydrofolate reductase 1 (MTHFR1); FUNCTIONS IN: methylenetetrahydrofolate reductase (NADPH) activity; INVOLVED IN: oxidation reduction, methionine metabolic process; EXPRESSED IN: fruit, guard cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Methylenetetrahydrofolate reductase (InterPro:IPR003171), Eukaryotic-type methylenetetrahydrofolate reductase (InterPro:IPR004621); BEST Arabidopsis thaliana protein match is: methylenetetrahydrofolate reductase 2 (TAIR:AT2G44160.1); Has 4753 Blast hits to 4742 proteins in 1927 species: Archae - 14; Bacteria - 3601; Metazoa - 134; Fungi - 280; Plants - 73; Viruses - 0; Other Eukaryotes - 651 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G59970-MONOMERBioCyc:ARA:GQT-1418-MONOMERBioCyc:ARA:GQT-258-MONOMEREC:1.5.1.20
eggNOG:COG0685eggNOG:KOG0564EMBL:AF181966EMBL:AL138647
EMBL:AY070034EMBL:AY122922EMBL:CP002686EnsemblPlants:AT3G59970
EnsemblPlants:AT3G59970.3entrez:825167ExpressionAtlas:Q9SE60Gene3D:3.20.20.220
GeneID:825167Genevisible:Q9SE60GO:GO:0004489GO:GO:0005829
GO:GO:0006730GO:GO:0009086GO:GO:0035999hmmpanther:PTHR21091
hmmpanther:PTHR21091:SF31HOGENOM:HOG000246234InParanoid:Q9SE60InterPro:IPR003171
InterPro:IPR004620InterPro:IPR004621InterPro:IPR029041iPTMnet:Q9SE60
KEGG:00670+1.5.1.20KEGG:00720+1.5.1.20KEGG:ath:AT3G59970KO:K00297
OMA:SIHDTFRPaxDb:Q9SE60Pfam:PF02219Pfam:Q9SE60
PhylomeDB:Q9SE60PIR:T47821PRIDE:Q9SE60PRO:PR:Q9SE60
ProteinModelPortal:Q9SE60Proteomes:UP000006548Reactome:R-ATH-196757RefSeq:NP_191556.1
RefSeq:NP_850723.1SABIO-RK:Q9SE60SMR:Q9SE60STRING:3702.AT3G59970.3
SUPFAM:SSF51730TAIR:AT3G59970tair10-symbols:MTHFR1TIGRfam:TIGR00676
TIGRfam:TIGR00677TIGRFAMs:TIGR00676TIGRFAMs:TIGR00677UniGene:At.1168
UniGene:At.23509UniGene:At.69007UniGene:At.72842UniPathway:UPA00193
UniProt:Q9SE60
Coordinates (TAIR10) chr3:+:22151303..22154323
Molecular Weight (calculated) 66291.90 Da
IEP (calculated) 5.56
GRAVY (calculated) -0.28
Length 592 amino acids
Sequence (TAIR10)
(BLAST)
001: MKVVDKIKSV TEQGQTAFSF EFFPPKTEDG VENLFERMDR LVSYGPTFCD ITWGAGGSTA DLTLEIASRM QNVICVETMM HLTCTNMPIE KIDHALETIR
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFAC ALDLVNHIRS KYGDYFGITV AGYPEAHPDV IEADGLATPE SYQSDLAYLK KKVDAGADLI VTQLFYDTDI
201: FLKFVNDCRQ IGINCPIVPG IMPISNYKGF LRMAGFCKTK IPAELTAALE PIKDNDEAVK AYGIHFATEM CKKILAHGIT SLHLYTLNVD KSAIGILMNL
301: GLIDESKISR SLPWRRPANV FRTKEDVRPI FWANRPKSYI SRTKGWNDFP HGRWGDSHSA AYSTLSDYQF ARPKGRDKKL QQEWVVPLKS IEDVQEKFKE
401: LCIGNLKSSP WSELDGLQPE TKIINEQLGK INSNGFLTIN SQPSVNAAKS DSPAIGWGGP GGYVYQKAYL EFFCSKDKLD TLVEKSKAFP SITYMAVNKS
501: ENWVSNTGES DVNAVTWGVF PAKEVIQPTI VDPASFKVWK DEAFEIWSRS WANLYPEDDP SRKLLEEVKN SYYLVSLVDN NYINGDIFSV FA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)