AT3G51770.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.889 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : tetratricopeptide repeat (TPR)-containing protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a negative regulator of 1-aminocyclopropane-1-carboxylic acid synthase5(ACS5), which catalyze the rate-limiting step in ethylene biosynthesis. ETO1 directly interacts with ACS5 and inhibits its enzyme activity and targets it for degradation via proteasome-dependent pathway. It also interacts with CUL3 (a component of ubiquitin ligase complexes). eto1 (and eto3) mutations elevate ethylene biosynthesis by affecting the posttranscriptional regulation of ACS | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ETHYLENE OVERPRODUCER 1 (ETO1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), BTB/POZ fold (InterPro:IPR011333), BTB/POZ-like (InterPro:IPR000210), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: ETO1-like 2 (TAIR:AT5G58550.1); Has 1321 Blast hits to 1075 proteins in 262 species: Archae - 34; Bacteria - 623; Metazoa - 134; Fungi - 2; Plants - 202; Viruses - 0; Other Eukaryotes - 326 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:-:19200328..19203998 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 108005.00 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.34 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.32 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 959 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MQHNLFTTMR SLKLAEGCKG TQVYALNPSA PTPPPPPGNS SSGGGGGGGS GGGTGGVGDK LLQHLSDHLR VNSVRSKSSR TYPPPTQPNA VVSPEFLLPC 101: GLPVTDLLEP QIDPCLKFVD LVEKMAQVYR RIENCSQFEK SGAYLEQCAI FRGISDPKLF RRSLRSSRQH AVDVHAKVVL ASWLRFERRE DELIGTTSMD 201: CCGRNLECPK ATLVSGYDPE SVYDPCVCSG ASRSEMMNED ECSTSQEVDY DMSFCIGDEE VRCVRYKIAS LSRPFKAMLY GGFREMKRAT INFTQNGISV 301: EGMRAAEIFS RTNRLDNFPP NVVLELLKLA NRFCCDELKS ACDSHLAHLV NSLDEAMLLI EYGLEEAAYL LVAACLQVFL RELPSSMHNP NVIKIFCSAE 401: GRERLASLGH ASFTLYFFLS QIAMEDDMKS NTTVMLLERL VECAVDSWEK QLAYHQLGVV MLERKEYKDA QRWFNAAVEA GHLYSLVGVA RTKFKRDHRY 501: SAYKIINSLI SDHKATGWMH QERSLYCSGK EKLLDLDTAT EFDPTLTFPY KFRAVALVEE NQFGAAIAEL NKILGFKASP DCLEMRAWIS IGMEDYEGAL 601: KDIRALLTLE PNFMMFNWKI HGDHMVELLR PLAQQWSQAD CWMQLYDRWS SVDDIGSLAV VHHMLANDPG KSLLRFRQSL LLLRLNCQKA AMRSLRLARN 701: HSKSEHERLV YEGWILYDTG HREEALAKAE ESISIQRSFE AFFLKAYALA DSTLDPDSSN YVIQLLQEAL KCPSDGLRKG QALNNLGSVY VDCEKLDLAA 801: DCYTNALTIK HTRAHQGLAR VYHLKNQRKA AYDEMTKLIE KAQNNASAYE KRSEYCDREM AQSDLCLATQ LDPLRTYPYR YRAAVLMDDH KESEAIDELS 901: RAISFKPDLQ LLHLRAAFYD SMGEGASAIK DCEAALCIDP GHADTLELYH KAREPNDQK |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)