AT3G51770.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : tetratricopeptide repeat (TPR)-containing protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a negative regulator of 1-aminocyclopropane-1-carboxylic acid synthase5(ACS5), which catalyze the rate-limiting step in ethylene biosynthesis. ETO1 directly interacts with ACS5 and inhibits its enzyme activity and targets it for degradation via proteasome-dependent pathway. It also interacts with CUL3 (a component of ubiquitin ligase complexes). eto1 (and eto3) mutations elevate ethylene biosynthesis by affecting the posttranscriptional regulation of ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ETHYLENE OVERPRODUCER 1 (ETO1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), BTB/POZ fold (InterPro:IPR011333), BTB/POZ-like (InterPro:IPR000210), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: ETO1-like 2 (TAIR:AT5G58550.1); Has 1321 Blast hits to 1075 proteins in 262 species: Archae - 34; Bacteria - 623; Metazoa - 134; Fungi - 2; Plants - 202; Viruses - 0; Other Eukaryotes - 326 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:-:19200328..19203974 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 107032.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.30 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.32 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 951 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MRSLKLAEGC KGTQVYALNP SAPTPPPPPG NSSSGGGGGG GSGGGTGGVG DKLLQHLSDH LRVNSVRSKS SRTYPPPTQP NAVVSPEFLL PCGLPVTDLL 101: EPQIDPCLKF VDLVEKMAQV YRRIENCSQF EKSGAYLEQC AIFRGISDPK LFRRSLRSSR QHAVDVHAKV VLASWLRFER REDELIGTTS MDCCGRNLEC 201: PKATLVSGYD PESVYDPCVC SGASRSEMMN EDECSTSQEV DYDMSFCIGD EEVRCVRYKI ASLSRPFKAM LYGGFREMKR ATINFTQNGI SVEGMRAAEI 301: FSRTNRLDNF PPNVVLELLK LANRFCCDEL KSACDSHLAH LVNSLDEAML LIEYGLEEAA YLLVAACLQV FLRELPSSMH NPNVIKIFCS AEGRERLASL 401: GHASFTLYFF LSQIAMEDDM KSNTTVMLLE RLVECAVDSW EKQLAYHQLG VVMLERKEYK DAQRWFNAAV EAGHLYSLVG VARTKFKRDH RYSAYKIINS 501: LISDHKATGW MHQERSLYCS GKEKLLDLDT ATEFDPTLTF PYKFRAVALV EENQFGAAIA ELNKILGFKA SPDCLEMRAW ISIGMEDYEG ALKDIRALLT 601: LEPNFMMFNW KIHGDHMVEL LRPLAQQWSQ ADCWMQLYDR WSSVDDIGSL AVVHHMLAND PGKSLLRFRQ SLLLLRLNCQ KAAMRSLRLA RNHSKSEHER 701: LVYEGWILYD TGHREEALAK AEESISIQRS FEAFFLKAYA LADSTLDPDS SNYVIQLLQE ALKCPSDGLR KGQALNNLGS VYVDCEKLDL AADCYTNALT 801: IKHTRAHQGL ARVYHLKNQR KAAYDEMTKL IEKAQNNASA YEKRSEYCDR EMAQSDLCLA TQLDPLRTYP YRYRAAVLMD DHKESEAIDE LSRAISFKPD 901: LQLLHLRAAF YDSMGEGASA IKDCEAALCI DPGHADTLEL YHKAREPNDQ K |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)