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AT3G16950.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : lipoamide dehydrogenase 1
Curator
Summary (TAIR10)
encodes a plastid lipoamide dehydrogenase, subunit of the pyruvate dehydrogenase complex which provides acetyl-CoA for de novo fatty acid biosynthesis. The gene is highly expressed in developing seeds.
Computational
Description (TAIR10)
lipoamide dehydrogenase 1 (LPD1); CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Pyridine nucleotide-disulphide oxidoreductase, class I, active site (InterPro:IPR012999), Pyridine nucleotide-disulphide oxidoreductase, dimerisation (InterPro:IPR004099), Dihydrolipoamide dehydrogenase (InterPro:IPR006258), FAD/NAD-linked reductase, dimerisation (InterPro:IPR016156), Mercuric reductase (InterPro:IPR000815), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327); BEST Arabidopsis thaliana protein match is: dihydrolipoyl dehydrogenases (TAIR:AT4G16155.1); Has 30222 Blast hits to 30191 proteins in 3051 species: Archae - 599; Bacteria - 20783; Metazoa - 811; Fungi - 386; Plants - 503; Viruses - 0; Other Eukaryotes - 7140 (source: NCBI BLink).
Protein Annotations
BioGrid:6284EC:1.8.1.4eggNOG:COG1249eggNOG:KOG1335
EMBL:AB026636EMBL:AF228637EMBL:AK317007EMBL:AY050376
EMBL:AY120695EMBL:CP002686EnsemblPlants:AT3G16950EnsemblPlants:AT3G16950.2
entrez:820951Gene3D:3.30.390.30Gene3D:3.50.50.60GeneID:820951
Genevisible:A8MS68GO:GO:0004148GO:GO:0005730GO:GO:0006086
GO:GO:0009507GO:GO:0009570GO:GO:0009941GO:GO:0045454
GO:GO:0046685GO:GO:0050660hmmpanther:PTHR22912hmmpanther:PTHR22912:SF165
HOGENOM:HOG000276708IntAct:A8MS68InterPro:IPR004099InterPro:IPR006258
InterPro:IPR012999InterPro:IPR016156InterPro:IPR023753KEGG:00010+1.8.1.4
KEGG:00020+1.8.1.4KEGG:00260+1.8.1.4KEGG:00280+1.8.1.4KEGG:00620+1.8.1.4
KEGG:00640+1.8.1.4KEGG:ath:AT3G16950KO:K00382OMA:RYADNTH
PaxDb:A8MS68Pfam:A8MS68Pfam:PF02852Pfam:PF07992
PhylomeDB:A8MS68PRIDE:A8MS68PRO:PR:A8MS68PROSITE:PS00076
ProteinModelPortal:A8MS68Proteomes:UP000006548RefSeq:NP_001078165.1RefSeq:NP_566562.1
scanprosite:PS00076SMR:A8MS68STRING:3702.AT3G16950.2SUPFAM:SSF51905
SUPFAM:SSF55424TAIR:AT3G16950tair10-symbols:LPD1tair10-symbols:ptlpd1
TIGRfam:TIGR01350TIGRFAMs:TIGR01350UniGene:At.16905UniProt:A8MS68
Coordinates (TAIR10) chr3:-:5786508..5790383
Molecular Weight (calculated) 66665.10 Da
IEP (calculated) 8.67
GRAVY (calculated) -0.09
Length 623 amino acids
Sequence (TAIR10)
(BLAST)
001: MQSAMALSFS QTSFTRPNHV LGSSGSVFST PRSLRFCGLR REAFGFSTSN QLAIRSNRIQ FLSRKSFQVS ASASSNGNGA PPKSFDYDLI IIGAGVGGHG
101: AALHAVEKGL KTAIIEGDVV GGTCVNRGCV PSKALLAVSG RMRELQNEHH MKSFGLQVSA AGYDRQGVAD HANNLATKIR NNLTNSMKAI GVDILTGFGS
201: VLGPQKVKYG KDNIITAKDI IIATGSVPFV PKGIEVDGKT VITSDHALKL ESVPEWIAIV GSGYIGLEFS DVYTALGSEV TFIEALDQLM PGFDPEISKL
301: AQRVLINPRK IDYHTGVFAS KITPARDGKP VLIELIDAKT KEPKDTLEVD AALIATGRAP FTNGLGLENV NVVTQRGFIP VDERMRVIDG KGTLVPNLYC
401: IGDANGKLML AHAASAQGIS VVEQVSGRDH VLNHLSIPAA CFTHPEISMV GLTEPQAKEK GEKEGFKVSV VKTSFKANTK ALAENEGEGI AKMIYRPDNG
501: EILGVHIFGL HAADLIHEAS NAIALGTRIQ DIKLAVHAHP TLSEVLDELF KAAKVESHAT TRTGDAKIKL NTNQEDRKGR RRGGDDEKQP SVSKDLKDIS
601: TRPSSFFENI SVGVLSLLSL IFV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)