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AT3G13080.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.989
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : multidrug resistance-associated protein 3
Curator
Summary (TAIR10)
encodes an ATP-dependent MRP-like ABC transporter able to transport glutathione-conjugates as well as chlorophyll catabolites. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.
Computational
Description (TAIR10)
multidrug resistance-associated protein 3 (MRP3); FUNCTIONS IN: chlorophyll catabolite transmembrane transporter activity, ATPase activity, coupled to transmembrane movement of substances, glutathione S-conjugate-exporting ATPase activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: apoplast, vacuolar membrane, plasma membrane, plant-type vacuole; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 8 (TAIR:AT3G13090.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
eggNOG:COG1132eggNOG:KOG0054EMBL:CP002686EnsemblPlants:AT3G13080
EnsemblPlants:AT3G13080.3EnsemblPlants:AT3G13080.4entrez:820496ExpressionAtlas:F4JB38
Gene3D:3.40.50.300GeneID:820496GO:GO:0005524GO:GO:0016021
GO:GO:0042626Gramene:AT3G13080.3Gramene:AT3G13080.4hmmpanther:PTHR24223
hmmpanther:PTHR24223:SF181InterPro:IPR003439InterPro:IPR003593InterPro:IPR011527
InterPro:IPR017871InterPro:IPR027417Pfam:PF00005Pfam:PF00664
Pfscan:PS50893Pfscan:PS50929PROSITE:PS00211PROSITE:PS50893
PROSITE:PS50929Proteomes:UP000006548RefSeq:NP_974299.1RefSeq:NP_974300.1
scanprosite:PS00211SMART:SM00382SMR:F4JB38STRING:3702.AT3G13080.1
SUPFAM:SSF52540SUPFAM:SSF90123TAIR:AT3G13080tair10-symbols:ABCC3
tair10-symbols:ATMRP3tair10-symbols:MRP3TMHMM:TMhelixUniGene:At.20479
UniProt:F4JB38
Coordinates (TAIR10) chr3:-:4197606..4201250
Molecular Weight (calculated) 124959.00 Da
IEP (calculated) 6.82
GRAVY (calculated) 0.27
Length 1120 amino acids
Sequence (TAIR10)
(BLAST)
0001: MDFLGSTTGS GTLAMLFSFS ESILPLDSRS FLLKPLFLRW LSGFLHSVLL LVLFFSWVRK KIRGDSGVTE SLKDRRDFGF KSALFCSLAL SLLNLVLMSL
0101: SGFYWYESGW LDNEQLVSSL GFLLGMVSWG VLSICLHRCR DCEHKKAPFL LRLWLVFYLV VSCYSLVVDF VMYERRETVP VHLLVFDIVA FIAAVFLGYV
0201: AVLKKDRSNS NGVLEEPLLN GGDSRVGGDD SVELNKTNGS GEATPYSRAG ILSLLTFSWM SPLIDIGNKK TLDLEDVPQL HDTDSVVGLA PKFRSMLESP
0301: DGGERSGVTT FKLIKALYFT AQWEILVTAF FAFIYTVASY VGPALIDTFV QYLNGRRQYN HEGYVLVITF FAAKIVECLS QRHWFFRLQK VGIRMRSALV
0401: AMIYEKGLTL SCQSKQGRTS GEIINFMTVD AERIGNFSWY MHDPWMVLLQ VGLALWILYR NLGLASIAAL VATIIVMLIN FPFGRMQERF QEKLMEAKDS
0501: RMKSTSEILR NMRILKLQGW EMKFLSKIFD LRKSEEGWLK KYVYNSAVIS FVFWGAPTLV SVSTFGACIL LGIPLESGKI LSALATFRIL QEPIYNLPDT
0601: ISMIVQTKVS LDRLASYLCL DNLQPDIVER LPKGSSDVAV EVINSTLSWD VSSSNPTLKD INFKVFPGMK VAVCGTVGSG KSSLLSSLLG EVPKVSGSLK
0701: VCGTKAYVAQ SPWIQSGKIE DNILFGKPME RERYDKVLEA CSLSKDLEIL SFGDQTVIGE RGINLSGGQK QRIQIARALY QDADIYLFDD PFSAVDAHTG
0801: SHLFKEVLLG LLCSKSVIYV THQVEFLPAA DLILVMKDGR ISQAGKYNDI LNSGTDFMEL IGAHQEALAV VDSVDANSVS EKSALGQENV IVKDAIAVDE
0901: KLESQDLKND KLESVEPQRQ IIQEEEREKG SVALDVYWKY ITLAYGGALV PFILLGQVLF QLLQIGSNYW MAWATPVSED VQAPVKLSTL MIVYVALAFG
1001: SSLCILLRAT LLVTAGYKTA TELFHKMHHC IFRSPMSFFD STPSGRIMSR ASTDQSAVDL ELPYQFGSVA ITVIQLIGII GVMSQVSWLV FLVFIPVVAA
1101: SIWYQVLFNK LYNLVFHKSC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)