AT3G04740.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : RNA polymerase II transcription mediators | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a protein with similarities to subunits of the Mediator complex, required for RNA polymerase II recruitment at target promoters in response to specific activators. Lines carrying loss of function mutations in the gene have reduced cell numbers in aerial organs. On the other hand, lines overexpressing the gene have increased number of small cells in clusters, suggesting cell division is more unsynchronized in the overexpressors. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
STRUWWELPETER (SWP); FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: positive regulation of transcription, positive regulation of cell proliferation; LOCATED IN: mediator complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med14 (InterPro:IPR013947); Has 940 Blast hits to 375 proteins in 163 species: Archae - 0; Bacteria - 61; Metazoa - 117; Fungi - 104; Plants - 74; Viruses - 0; Other Eukaryotes - 584 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:1294037..1300555 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 185519.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.43 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.13 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1703 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MAELGQQTVD FSALVGRAAE ESFLSFKELV DKSKSTELSD TEKKVSLLKY VAKTQQRMLR LNALAKWCKQ VPLINYFQDL GSTLSAHDIC FTQAADSLFF 0101: MHEGLQQARA PVYDVPSAVE ILLTGSYQRL PKCLDDVGMQ SSLDEHQQKP ALRKLEVLVR SKLLEITLPK EITEVKISKG TVTLSVDGEF KVLVTLGYRG 0201: HLSMWRILHL DLLVGERSGP IKLEVTRRHI LGDDLERRMS VAENPFTILY AVLHELCVAI VMDTVIRQVR ALLQGRWKDA IRFDLISDTG TTPANQEGEA 0301: DSVSLRTPGM KLFYWSDSDK NSGPFIKIEP GSDLQIKCSH STFVIDPLTG KEAEFSLDQS CIDVEKLLLK AICCNRYTRL LEIQKELLRN TRICRTPSDV 0401: ILQALLDEPG IEGDNMVDSK ERVEPEVLRV RAYGSSFFTL GINIRTGRFL LQSSKSILTS SILEEFEDAL NQGSISAVDA FINLRSKSIL HFFAAIGKFL 0501: GLEVYEHGFG INKVPKSLLD GSSILTLGFP DCESSHLLLM ELEKDFTPLF KLLETQMDGS GKPQSFNDPS NILRAKKIDI GQIRILEDDL NLITSDVVKF 0601: VSSFSDAEGI NQASGHRQPG LVDEALTEMS GSQLSFSSVV DGVFGLQKVT SALMSIDGHG LVPKNLSAVT GHGKAPMLTS YHSDSLYNRQ GPLQSSSYNM 0701: LSSPPGKGSA MKKIAISNSD QELSLILSPS LSTGNGVSES GSRLVTESSL SPLPLSQTAD LATSSAGPLL RKDQKPRKRS ASDLLRLIPS LQVVEGVASP 0801: NKRRKTSELV QSELVKSWSP ASQTLSTAVS TSTKTIGCSY GNLIAEANKG NAPSSVFVYA LLHVVRHSSL SIKHAKLTSQ MEALDIQYVE EMGLRDAFSD 0901: IWFRLPFAQN DSWQHICLQL GRPGSMCWDV KINDQHFRDL WELQKGSKTT PWGSGVHIAN SSDVDSHIRY DPEGVVLSYQ SVEADSIKKL VADIQRLSNA 1001: RMFSLGMRKL LGIKPDEKTE ECSANSTMKG STGGKGSGEP VDRWRAFKIE AVGLTSLWFS FGSGVLARFV VEWESGKDGC TMHVSPDQLW PHTKFLEDFI 1101: NGAEVESLLD CIRLTAGPLH ALAAATRPAR ASTATGMPVV PATASSRQSN QIQQTQGIIA PSTLAAPNAT GQSASATSGN TVASSAPSPL GGGFHGVAML 1201: AAAGRSGPGI VPSSLLPIDV SVVLRGPYWI RIIYRKRFAV DMRCFAGDQV WLQPATPPKG GASIGGSLPC PQFRPFIMEH VAQELNGLEP NLTGSQGATN 1301: PNSGNPTVNG VNRVNFSPSS ARAAMNRVAS VASGSLVVSS GLPVRRTPGT AVPAHVRGEL NTAIIGLGDD GGYGGGWVPL VALKKVLRGI LKYLGVLWLF 1401: AQLPDLLREI LGSILKDNEG ALLNLDQEQP ALRFFVGGYV FAVSVHRVQL LLQVLSVRRF HHQAQQNGSS AAAQEELTQS EIGEICDYFS RRVASEPYDA 1501: SRVASFITLL TLPISVLREF LKLIAWKKGL SQSQQAGEIA PAQRPRIELC LENHSGTDLD NNCAAKSNIH YDRPHNTVDF ALTVVLDPVH IPHINAAGGA 1601: AWLPYCVSVR LRYTFGENPS VTFLGMEGSH GGRACWQRVD DWEKCKQRVS RTVEVNGSAA GDLTQGKLKL VADSVQRTLH LCLQGLREGG NNNNNTHQKE 1701: FTI |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)