AT3G04280.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:cytosol 0.500 nucleus 0.500 ASURE: cytosol,nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : response regulator 22 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes an atypical subtype of the ARR (Arabidopsis response regulator) protein family. ARR22 is more similar to the receiver domains of hybrid kinases than other response regulators. It acts as a phosphohistidine phosphatase when tested with phospho-AHP5 in vitro suggesting that it might be involved in a two-component phosphorelay. Expression of ARR22 transcripts appears to be localized to the chalaza and to be induced by wounding. Ectopic expression of ARR in other parts of the plant leads to reduced cytokinin-related responses and impaired root, shoot, and flower development. Overexpression of wild-type ARR22 in an arr22 mutant background causes variable defects in plant growth and fertility. But, in the same ar22 background, over-expression of versions of ARR22 that should act as dominant-negative or constitutively active proteins, based on mutations to the conserved Asp residue, do not show any phenotypic abnormalities, raising the possibility that these may not act as canonical response regulators. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
response regulator 22 (RR22); CONTAINS InterPro DOMAIN/s: CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789); BEST Arabidopsis thaliana protein match is: response regulator 24 (TAIR:AT5G26594.1); Has 38320 Blast hits to 37605 proteins in 2640 species: Archae - 260; Bacteria - 34018; Metazoa - 17; Fungi - 1133; Plants - 527; Viruses - 9; Other Eukaryotes - 2356 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr3:-:1130138..1130689 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 15793.30 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 6.96 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.31 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 142 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MATKSTGGTE KTKSIEVKKK LINVLIVDDD PLNRRLHEMI IKTIGGISQT AKNGEEAVIL HRDGEASFDL ILMDKEMPER DGVSTTKKLR EMKVTSMIVG 101: VTSVADQEEE RKAFMEAGLN HCLEKPLTKA KIFPLISHLF DA |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)