AT2G47470.4
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : thioredoxin family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
UNFERTILIZED EMBRYO SAC 5 (UNE5); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress, double fertilization forming a zygote and endosperm, embryo sac development, pollen tube development, embryo development ending in seed dormancy; LOCATED IN: endoplasmic reticulum, plasma membrane, plant-type cell wall; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Endoplasmic reticulum, protein ERp29, C-terminal (InterPro:IPR011679), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 37639 Blast hits to 19288 proteins in 2969 species: Archae - 403; Bacteria - 17566; Metazoa - 6414; Fungi - 2106; Plants - 3416; Viruses - 32; Other Eukaryotes - 7702 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:19481503..19483683 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 36566.40 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 5.34 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.26 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 335 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAKSQIWFGF ALLALLLVSA VADDVVVLTD DSFEKEVGKD KGALVEFYAP WCGHCKKLAP EYEKLGASFK KAKSVLIAKV DCDEQKSVCT KYGVSGYPTI 101: QWFPKGSLEP QKYEGPRNAE ALAEYVNKEG GTNVKLAAVP QNVVVLTPDN FDEIVLDQNK DVLVEFYAPW CGHCKSLAPT YEKVATVFKQ EEGVVIANLD 201: ADAHKALGEK YGVSGFPTLK FFPKDNKAGH DYDGGRDLDD FVSFINEKSG TSRDSKGQLT SKAGIVESLD ALVKELVAAS EDEKKAVLSR IEKGSDYASK 301: ETERLGRVLG KSISPVKADE LTLKRNILTT FVASS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)