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AT2G38170.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 0.806
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : cation exchanger 1
Curator
Summary (TAIR10)
Encodes a high affinity vacuolar calcium antiporter. The residue His 338 is critical to Ca2+ transport activity. Disruption of CAX1 reduces manganese and zinc of shoot tissue and results in a decrease in the activity of vacuolar V-type proton ATPase.
Computational
Description (TAIR10)
cation exchanger 1 (CAX1); FUNCTIONS IN: calcium:cation antiporter activity, calcium ion transmembrane transporter activity, calcium:hydrogen antiporter activity; INVOLVED IN: cold acclimation, response to salt stress, cellular zinc ion homeostasis, cellular manganese ion homeostasis, calcium ion transport; LOCATED IN: plant-type vacuole membrane, vacuolar membrane, vacuole, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sodium/calcium exchanger membrane region (InterPro:IPR004837), Calcium/proton exchanger (InterPro:IPR004713); BEST Arabidopsis thaliana protein match is: cation exchanger 3 (TAIR:AT3G51860.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0387eggNOG:KOG1397EMBL:CP002685EnsemblPlants:AT2G38170
EnsemblPlants:AT2G38170.2entrez:818395ExpressionAtlas:F4IS06GeneID:818395
GO:GO:0015369GO:GO:0016021Gramene:AT2G38170.2hmmpanther:PTHR31503
hmmpanther:PTHR31503:SF1InterPro:IPR004713InterPro:IPR004798InterPro:IPR004837
PaxDb:F4IS06Pfam:PF01699PRIDE:F4IS06ProteinModelPortal:F4IS06
Proteomes:UP000006548RefSeq:NP_850292.2SMR:F4IS06STRING:3702.AT2G38170.3
TAIR:AT2G38170tair10-symbols:ATCAX1tair10-symbols:CAX1tair10-symbols:RCI4
TIGRfam:TIGR00378TIGRfam:TIGR00846TIGRFAMs:TIGR00378TIGRFAMs:TIGR00846
TMHMM:TMhelixUniGene:At.12459UniProt:F4IS06
Coordinates (TAIR10) chr2:-:15990574..15993178
Molecular Weight (calculated) 43300.10 Da
IEP (calculated) 6.52
GRAVY (calculated) 0.46
Length 392 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGIVTEPWS VAENGNPSIT AKGSSRELRL GRTAHNMSSS SLRKKSDLRV IQKVPYKGLK DFLSNLQEVI LGTKLAILFP AIPAAIICTY CGVSQPWIFG
101: LSLLGLTPLA ERVSFLTEQL AFYTGPTLGG LLNATCGNAT ELIIAILALT NNKVAVVKYS LLGSILSNLL LVLGTSLFCG GIANIRREQR FDRKQADVNF
201: FLLLLGFLCH LLPLLVGYLK NGEASAAVLS DMQLSISRGF SIVMLISYIA YLVFQLWTHR QLFDAQEQED EYDDDVEQET AVISFWSGFA WLVGMTLVIA
301: LLSEYVVATI EEASDKWNLS VSFISIILLP IVGNAAEHAG AVIFAFKNKL VSSILFLKII AFNRSRDLLY NDTMQELISI QIISRTYLWE LR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)