AT2G31970.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : DNA repair-recombination protein (RAD50) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes the Arabidopsis RAD50 homologue. It is involved in double strand break repair. Component of the meiotic recombination complex that processes meiotic double-strand-breaks to produce single-stranded DNA ends, which act in the homology search and recombination. Accumulates in the nucleus during meiotic prophase, a process regulated by PHS1. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
RAD50; FUNCTIONS IN: zinc ion binding, ATP binding, nuclease activity; INVOLVED IN: DNA repair, double-strand break repair, telomere capping, mitotic recombination, telomere maintenance; LOCATED IN: nucleus, Mre11 complex, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Zinc hook, Rad50 (InterPro:IPR013134), Rad50 zinc hook (InterPro:IPR007517), Recombination/repair protein Rad50 (InterPro:IPR004584); Has 105617 Blast hits to 56308 proteins in 2913 species: Archae - 1820; Bacteria - 19240; Metazoa - 45759; Fungi - 8381; Plants - 4805; Viruses - 470; Other Eukaryotes - 25142 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:13600657..13608815 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 152823.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 6.21 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.80 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 1316 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
0001: MSTVDKMLIK GIRSFDPENK NVVTFFRPLT LIVGANGAGK TTIIECLKVS CTGELPPNAR SGHSFIHDPK VAGETETKAQ IKLRFKTAAG KDVVCIRSFQ 0101: LTQKASKMEY KAIESVLQTI NPHTGEKVCL SYRCADMDRE IPALMGVSKA ILENVIFVHQ DESNWPLQDP STLKKKFDDI FSATRYTKAL EVIKKLHKDQ 0201: AQEIKTFKLK LENLQTLKDA AYKLRESIAQ DQERTESSKV QMLELETSVQ KVDAEVHNKE MMLKDLRKLQ DQVSIKTAER STLFKEQQRQ YAALPEENED 0301: TIEELKEWKS KFEERLALLG TKIRKMEREM VDTETTISSL HNAKTNYMLE ISKLQTEAEA HMLLKNERDS TIQNIFFHYN LGNVPSTPFS TEVVLNLTNR 0401: IKSRLGELEM DLLDKKKSNE TALSTAWDCY MDANDRWKSI EAQKRAKDEI KMGISKRIEE KEIERDSFEF EISTVDVKQT DEREKQVQVE LERKTKQNSE 0501: RGFESKIEQK QHEIYSLEHK IKTLNRERDV MAGDAEDRVK LSLKKTEQEN LKKKHKKIID ECKDRIRGVL KGRLPPEKDM KREIVQALRS IEREYDDLSL 0601: KSREAEKEVN MLQMKIQEVN NSLFKHNKDT ESRKRYIESK LQALKQESVT IDAYPKLLES AKDKRDDRKR EYNMANGMRQ MFEPFEKRAR QEHSCPCCER 0701: SFTADEEASF IKKQRVKASS TGEHLKALAV ESSNADSVFQ QLDKLRAVFE EYSKLTTEII PLAEKTLQEH TEELGQKSEA LDDVLGISAQ IKADKDSIEA 0801: LVQPLENADR IFQEIVSYQK QIEDLEYKLD FRGLGVKTME EIQSELSSLQ SSKDKLHGEL EKLRDDQIYM ERDISCLQAR WHAVREEKAK AANLLRDVTK 0901: AEEDLERLAE EKSQLDLDVK YLTEALGPLS KEKEQLLSDY NDMKIRRNQE YEELAEKKRN YQQEVEALLK ASYKINEYHD LKKGERLDDI QEKQRLSDSQ 1001: LQSCEARKNE LAGELNRNKD LMRNQDQLRR NIEDNLNYRT TKAKVEELTR EIESLEEQIL NIGGIAAVEA EIVKILRERE RLLSELNRCR GTVSVYESSI 1101: SKNRVELKQA QYKDIDKRHF DQLIQLKTTE MANKDLDRYY NALDKALMRF HTMKMEEINK IIRELWQQTY RGQDMDYIRI HSDSEGAGTR SYSYKVLMQT 1201: GDTELEMRGR CSAGQKVLAS LIIRLALAET FCLNCGILAL DEPTTNLDGP NSESLAGALL RIMEDRKGQE NFQLIVITHD ERFAQMIGQR QHAEKYYRVA 1301: KDDMQHSIIE AQEIFD |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)