AT2G27120.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : DNA polymerase epsilon catalytic subunit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein with similarity to DNA polymerase epsilon catalytic subunit. Based on yeast two hybrid analysis, not predicted to be a subunit of the DNA polymerase epsilon complex. No phenotype observed in homozygous mutant embryos or plants but in combination with TIL1-1/til1-1 heterozygotes arrest earlier than til1 homozygotes suggesting TIL2 functions redundantly with TIL1. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
TILTED 2 (TIL2); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: DNA replication; EXPRESSED IN: leaf whorl, sperm cell, male gametophyte, flower, pollen tube; EXPRESSED DURING: M germinated pollen stage, 4 anthesis; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT1G08260.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:11581223..11594346 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 245006.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.88 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.32 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 2138 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MSGRRCDRRL NVQKVSAADE LETKLGFGLF SQGETRLGWL LTFASSSWED ADTGKTFSCV DLFFVTQDGS SFKTKYKFRP YLYAATKDNM ELEVEAYLRR 0101: RYERQVADIQ IVHKEDLYLK NHLSGLQKKY LKVSFDTVQQ LVEVKRDLLH IVERNLAKFN ALEAYESILS GKREQRPQDC LDSVVDLREY DVPYHVRFAI 0201: DNDVRSGQWY NVSISSTDVI LEKRTDLLQR AEVRVCAFDI ETVKLPLKFP DAEYDQIMMI SYMVDGQGFL ITNRECVGKD IEDLEYTPKP EFEGYFKVTN 0301: VTNEVELLRK WFSHMQELKP GIYVTYNGDF FDWPFIERRA SHHGIKMNEE LGFRCDQNQG ECRAKFVCHL DCFSWVKRDS YLPQGSQGLK AVTKVKLGYD 0401: PLEVNPEDMV RFAMEKPQTM ASYSVSDAVA TYYLYMTYVH PFVFSLATII PMVPDEVLRK GSGTLCEMLL MVEAYKANVV CPNKNQADPE KFYQGKLLES 0501: ETYIGGHVEC LQSGVFRSDI PTSFKLDASA YQQLIDNLGR DLEYAITVEG KMRMDSVSNF DEVKEVIREK LEKLRDDPIR EEGPLIYHLD VAAMYPNIIL 0601: TNRLQPPSIV TDEVCTACDF NGPEKTCLRK LEWVWRGVTF KGNKSEYYHL KKQIESESVD AGANMQSSKP FLDLPKVEQQ SKLKERLKKY CQKAYSRVLD 0701: KPITEVREAG ICMRENPFYV DTVRSFRDRR YEYKTLNKVW KGKLSEAKAS GNLIKIQEAH DMVVVYDSLQ LAHKCILNSF YGYVMRKGAR WYSMEMAGVV 0801: TYTGAKIIQN ARLLIERIGK PLELDTDGIW CALPGSFPEN FTFKTIDMKK FTISYPCVIL NVDVAKNNSN DQYQTLVDPV RKTYNSRSEC SIEFEVDGPY 0901: KAMIIPASKE EGILIKKRYA VFNHDGTIAE LKGFEMKRRG ELKLIKVFQA ELFDKFLHGS TLEECYSAVA AVANRWLDLL EGQGKDIADS ELLDYISESS 1001: TMSKSLADYG QQKSCAVTTA KRLADFLGDT MVKDKGLRCQ YIVAREPEGT PVSERAVPVA IFQTDDPEKK FYLQKWCKIS SYTGIRSIID WMYYKQRLHS 1101: AIQKVITIPA AMQKVANPVL RVRHPYWLEK KVCDKFRQGK IVDMFSSANK DHSTTQDNVV ADIEEFCKEN RPSVKGPKPV ARSFEVDRNH SEGKQQESWD 1201: PEFHDISLQN VDKNVDYQGW LELEKRKWKM TLTNKKKRRY SSSLFGFDLE QNINKKVCKG RVGVGSYFRR PEEALTSSYL QIIQLVQSPQ SGQFFAWVVV 1301: EGLMLKIPLT IPRVFYINSK ASIAGNFTGK CINKILPHGK PCYNLMEVNI QEDQFIKESK KLAALLADPE IEGIYETKMP LEFSAICQIG CVCKIEDTAK 1401: HRNTQDGWKL GELHRITTTE CRYLENSIPL VYLYHSTSTG RAVYVLYCHA SKLMSVVVVN PYGDKELLSS ALERQFRDRC QELSPEPFSW DGILFQVEYV 1501: DHPEAATKFL QKALCEYREE NCGATVAVIE CPDFNTTKEG VKALEDFPCV RIPFNDDDNS YQPVSWQRPA AKIAVLRCAS AIQWLDRRIA QSRYAHVPLG 1601: NFGRDWLTFT VDIFLSRALR DQQQVLWVSD NGVPDLGDIN NEETFLADET SLLFPGAYRK VSVELKVHRL AVNALLKSDL VSEMEGGGFL GVNSRGSSLN 1701: DNGSFDENNG CAQAFRVLKQ LIKRLLHDAC NSGNIYADSI LQHLSWWLRS PSSKLHDPAL HLMLHKVMQK VFALLLTDLR RLGAIIIYAD FSKVIIDTGK 1801: FDLSAAKTYC ESLLTVMGSR DIFKLILLEP VHYWHSLLFM DQHNYAGIRA TGDEISGNEV TIEPKWSVAR HLPEYIQKDF IIIVATFIFG PWKFALEKKR 1901: GSAESLEAEM VEYLKEQIGT RFISMIVEKI GNIRSHIKDI NVSDASWASG QAPKGDYTFE FIQIITAVLA LDQNVQQDVL VMRKILLKYI KVKECAAEAE 2001: FIDPGPSFIL PNVACSNCGA YRDLDFCRDS ALLTEKEWSC ADPQCVKIYD KEQIESSIIQ MVRQRERMYQ LQDLVCNRCN QVKAAHLTEQ CECSGSFRCK 2101: ESGSDFHKRI EIFLDIAKRQ KFRLLEECIS WILFATSC |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)