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AT2G24740.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : SET domain group 21
Curator
Summary (TAIR10)
Encodes a SU(VAR)3-9 homolog, a SET domain protein (Homology Subgroup V; Orthology Group 1). Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. This protein is a putative histone methyltransferase (predicted to methylate H3K9/20) related to the the Drosophila Su(var)3-9 and mammalian G9a proteins.
Computational
Description (TAIR10)
SET domain group 21 (SDG21); FUNCTIONS IN: histone methyltransferase activity; INVOLVED IN: regulation of gene expression, epigenetic; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), AT hook, DNA-binding motif (InterPro:IPR017956), SRA-YDG (InterPro:IPR003105), Pre-SET zinc-binding sub-group (InterPro:IPR003606), Pre-SET domain (InterPro:IPR007728), Post-SET domain (InterPro:IPR003616); BEST Arabidopsis thaliana protein match is: SU(VAR)3-9 homolog 7 (TAIR:AT1G17770.1); Has 4288 Blast hits to 4094 proteins in 395 species: Archae - 0; Bacteria - 274; Metazoa - 2162; Fungi - 458; Plants - 1048; Viruses - 4; Other Eukaryotes - 342 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G24740-MONOMEREC:2.1.1.43eggNOG:COG2940eggNOG:COG3440
eggNOG:KOG1082EMBL:AC007266EMBL:AF344451EMBL:CP002685
EnsemblPlants:AT2G24740EnsemblPlants:AT2G24740.1entrez:817010Gene3D:2.30.280.10
GeneID:817010Genevisible:Q9C5P0GO:GO:0000775GO:GO:0003677
GO:GO:0005634GO:GO:0008270GO:GO:0008361GO:GO:0018024
GO:GO:0040029GO:GO:0042054GO:GO:0048366Gramene:AT2G24740.1
hmmpanther:PTHR22884hmmpanther:PTHR22884:SF383HOGENOM:HOG000238382InParanoid:Q9C5P0
InterPro:IPR001214InterPro:IPR003105InterPro:IPR003616InterPro:IPR007728
InterPro:IPR015947InterPro:IPR025794iPTMnet:Q9C5P0KEGG:ath:AT2G24740
KO:K11420OMA:TASTNCMPaxDb:Q9C5P0Pfam:PF00856
Pfam:PF02182Pfam:PF05033Pfam:Q9C5P0Pfscan:PS50280
Pfscan:PS50868Pfscan:PS51015Pfscan:PS51575PhylomeDB:Q9C5P0
PIR:C84640PRIDE:Q9C5P0PRO:PR:Q9C5P0PROSITE:PS50280
PROSITE:PS50868PROSITE:PS51015PROSITE:PS51575ProteinModelPortal:Q9C5P0
Proteomes:UP000006548RefSeq:NP_180049.2SMART:SM00317SMART:SM00466
SMART:SM00468SMR:Q9C5P0STRING:3702.AT2G24740.1SUPFAM:SSF82199
SUPFAM:SSF88697TAIR:AT2G24740tair10-symbols:SDG21tair10-symbols:SUVH8
UniGene:At.66241UniProt:Q9C5P0
Coordinates (TAIR10) chr2:-:10529690..10531957
Molecular Weight (calculated) 84532.40 Da
IEP (calculated) 6.13
GRAVY (calculated) -0.65
Length 755 amino acids
Sequence (TAIR10)
(BLAST)
001: MVSTPPTLLM LFDDGDAGPS TGLVHREKSD AVNEEAHATS VPPHAPPQTL WLLDNFNIED SYDRDAGPST GPVHRERSDA VNEEAHATSI PPHAPPQTLW
101: LLDNFNIEDS YDRDAGPSTS PIDREASHEV NEDAHATSAP PHVMVSPLQN RRPFDQFNNQ PYDASAGPST GPGKRGRGRP KGSKNGSRKP KKPKAYDNNS
201: TDASAGPSSG LGKRRCGRPK GLKNRSRKPK KPKADDPNSK MVISCPDFDS RITEAERESG NQEIVDSILM RFDAVRRRLC QLNYRKDKIL TASTNCMNLG
301: VRTNMTRRIG PIPGVQVGDI FYYWCEMCLV GLHRNTAGGI DSLLAKESGV DGPAATSVVT SGKYDNETED LETLIYSGHG GKPCDQVLQR GNRALEASVR
401: RRNEVRVIRG ELYNNEKVYI YDGLYLVSDC WQVTGKSGFK EYRFKLLRKP GQPPGYAIWK LVENLRNHEL IDPRQGFILG DLSFGEEGLR VPLVNEVDEE
501: DKTIPDDFDY IRSQCYSGMT NDVNVDSQSL VQSYIHQNCT CILKNCGQLP YHDNILVCRK PLIYECGGSC PTRMVETGLK LHLEVFKTSN CGWGLRSWDP
601: IRAGTFICEF TGVSKTKEEV EEDDDYLFDT SRIYHSFRWN YEPELLCEDA CEQVSEDANL PTQVLISAKE KGNVGRFMNH NCWPNVFWQP IEYDDNNGHI
701: YVRIGLFAMK HIPPMTELTY DYGISCVEKT GEDEVIYKGK KICLCGSVKC RGSFG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)