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AT2G21660.2
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:22550958 (2012): plastid
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : cold, circadian rhythm, and rna binding 2
Curator
Summary (TAIR10)
Encodes a small glycine-rich RNA binding protein that is part of a negative-feedback loop through which AtGRP7 regulates the circadian oscillations of its own transcript. Gene expression is induced by cold. GRP7 appears to promote stomatal opening and reduce tolerance under salt and dehydration stress conditions, but, promotes stomatal closing and thereby increases stress tolerance under conditions of cold tolerance. Loss of function mutations have increased susceptibility to pathogens suggesting a role in mediating innate immune response. Mutants are also late flowering in a non-photoperiodic manner and are responsive to vernalization suggesting an interaction with the autonomous flowering pathway. There is a reduction of mRNA export from the nucleus in grp7 mutants. GRP7:GFP fusion proteins can be found in the cytosol and nucleus. A substrate of the type III effector HopU1 (mono-ADP-ribosyltransferase).
Computational
Description (TAIR10)
GLYCINE RICH PROTEIN 7 (ATGRP7); FUNCTIONS IN: double-stranded DNA binding, RNA binding, single-stranded DNA binding; INVOLVED IN: in 12 processes; LOCATED IN: nucleus, chloroplast, peroxisome, cytoplasm; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, glycine rich protein (InterPro:IPR015465), RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: cold, circadian rhythm, and RNA binding 1 (TAIR:AT4G39260.3); Has 381 Blast hits to 381 proteins in 95 species: Archae - 0; Bacteria - 0; Metazoa - 191; Fungi - 60; Plants - 124; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0724eggNOG:KOG0118EMBL:CP002685EnsemblPlants:AT2G21660
EnsemblPlants:AT2G21660.2entrez:816705ExpressionAtlas:F4IHK9Gene3D:3.30.70.330
GeneID:816705GO:GO:0000166GO:GO:0003676Gramene:AT2G21660.2
hmmpanther:PTHR24012InterPro:IPR000504InterPro:IPR012677PaxDb:F4IHK9
Pfam:PF00076Pfscan:PS50102PRIDE:F4IHK9PROSITE:PS50102
ProteinModelPortal:F4IHK9Proteomes:UP000006548RefSeq:NP_850017.1SMART:SM00360
SMR:F4IHK9STRING:3702.AT2G21660.1SUPFAM:SSF54928TAIR:AT2G21660
tair10-symbols:ATGRP7tair10-symbols:CCR2UniGene:At.22672UniGene:At.23628
UniGene:At.24279UniGene:At.72988UniProt:F4IHK9
Coordinates (TAIR10) chr2:-:9265477..9266316
Molecular Weight (calculated) 15549.50 Da
IEP (calculated) 5.25
GRAVY (calculated) -0.75
Length 159 amino acids
Sequence (TAIR10)
(BLAST)
001: MASGDVEYRC FVGGLAWATD DRALETAFAQ YGDVIDSKII NDRETGRSRG FGFVTFKDEK AMKDAIEGMN GQDLDGRSIT VNEAQSRGSG GGGGHRGGGS
101: YGGGGGRREG GGGYSGGGGG YSSRGGGGGS YGGGRREGGG GYGGGEGGGY GGSGGGGGW
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)