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AT2G21170.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:23851315 (2013): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : triosephosphate isomerase
Curator
Summary (TAIR10)
Encodes a plastidic triose phosphate isomerase. Mutants with reduced pdTPI levels have difficulty transitioning from heterotrophic to autotrophic growth. The related phenotypes, such as chlorosis in light-grown seedlings may result from an accumulation of dihydroxyacetone phosphate (DHAP) and methylglyoxal (MG) in these mutants. Both splice variants appear to be expressed, but the At2g21170.2 variant appears to have a much narrower expression range limited to roots.
Computational
Description (TAIR10)
triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11527 Blast hits to 11525 proteins in 3623 species: Archae - 144; Bacteria - 6185; Metazoa - 1204; Fungi - 240; Plants - 472; Viruses - 0; Other Eukaryotes - 3282 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0149eggNOG:KOG1643EMBL:CP002685EnsemblPlants:AT2G21170
EnsemblPlants:AT2G21170.2entrez:816652ExpressionAtlas:A8MRE8Gene3D:3.20.20.70
GeneID:816652GO:GO:0004807GO:GO:0006096Gramene:AT2G21170.2
gramene_pathway:5.3.1.1gramene_pathway:CALVIN-PWYgramene_pathway:GLYCOLYSISgramene_pathway:PWY-1042
gramene_plant_reactome:1119424gramene_plant_reactome:1119519gramene_plant_reactome:6876923gramene_plant_reactome:6877176
HAMAP:MF_00147_Bhmmpanther:PTHR21139hmmpanther:PTHR21139:SF7HOGENOM:HOG000226413
InterPro:IPR000652InterPro:IPR013785InterPro:IPR020861InterPro:IPR022896
KEGG:00010+5.3.1.1KEGG:00051+5.3.1.1KEGG:00562+5.3.1.1KEGG:00710+5.3.1.1
KEGG:ath:AT2G21170KO:K01803PANTHER:PTHR21139PaxDb:A8MRE8
Pfam:PF00121Pfscan:PS51440PRIDE:A8MRE8ProMEX:A8MRE8
PROSITE:PS00171PROSITE:PS51440ProteinModelPortal:A8MRE8Proteomes:UP000006548
RefSeq:NP_001077931.1scanprosite:PS00171SMR:A8MRE8STRING:3702.AT2G21170.1
SUPFAM:SSF51351TAIR:AT2G21170tair10-symbols:PDTPItair10-symbols:TIM
TIGRfam:TIGR00419TIGRFAMs:TIGR00419UniGene:At.24668UniGene:At.31909
unipathway:UPA00109unipathway:UPA00138UniProt:A8MRE8
Coordinates (TAIR10) chr2:-:9071047..9073106
Molecular Weight (calculated) 32308.20 Da
IEP (calculated) 7.60
GRAVY (calculated) -0.08
Length 306 amino acids
Sequence (TAIR10)
(BLAST)
001: MAATSLTAPP SFSGLRRISP KLDAAAVSSH QSFFHRVNSS TRLVSSSSSS HRSPRGVVAM AGSGKNGTKD SIAKLISDLN SATLEADVDV VVSPPFVYID
101: QVKSSLTDRI DISGQNSWVG KGGAFTGEIS VEQLKDLGCK WVILGHSERR HVIGEKDEFI GKKAAYALSE GLGVIACIGE KLEEREAGKT FDVCFAQLKA
201: FADAVPSWDN IVVAYEPVWA IGTGKVASPQ QAQEVHVAVR GWLKKNVSEE VASKTRIIYG GSVNGGNSAE LAKEEDIDGF LVGGASLKGP EFATIVNSVT
301: SKKVAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)