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AT2G20000.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : CDC27 family protein
Curator
Summary (TAIR10)
Required for cell division and cell differentiation in meristems. Encodes a homolog of the CDC27 subunit of the anaphase-promoting complex (APC). Unlike other CDC27 homologs in Arabidopsis, its transcription is cell cycle regulated. Strong hbt mutants give rise to seedlings that lack an anatomically recognizable quiescent center and differentiated columella root cap cells, the cell types derived from the wild-type hypophysis. Furthermore, they have no mitotically active root meristem and lack a differentiated lateral root cap.
Computational
Description (TAIR10)
HOBBIT (HBT); FUNCTIONS IN: binding; INVOLVED IN: in 10 processes; LOCATED IN: anaphase-promoting complex, nucleus, cell plate, spindle; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G16320.1); Has 19127 Blast hits to 10740 proteins in 1344 species: Archae - 1126; Bacteria - 9300; Metazoa - 1888; Fungi - 782; Plants - 572; Viruses - 0; Other Eukaryotes - 5459 (source: NCBI BLink).
Protein Annotations
BioGrid:1874eggNOG:COG0457eggNOG:KOG1126EMBL:AC006081
EMBL:AJ487669EMBL:AY062470EMBL:AY128780EMBL:CP002685
EnsemblPlants:AT2G20000EnsemblPlants:AT2G20000.1entrez:816519GeneID:816519
Genevisible:Q8LGU6GO:GO:0005634GO:GO:0005680GO:GO:0005819
GO:GO:0007067GO:GO:0007346GO:GO:0009504GO:GO:0009733
GO:GO:0010071GO:GO:0016567GO:GO:0030154GO:GO:0048364
GO:GO:0048829GO:GO:0051301Gramene:AT2G20000.1hmmpanther:PTHR12558
hmmpanther:PTHR12558:SF13HOGENOM:HOG000231056InParanoid:Q8LGU6IntAct:Q8LGU6
InterPro:IPR001440InterPro:IPR011990InterPro:IPR013026InterPro:IPR019734
iPTMnet:Q8LGU6KEGG:ath:AT2G20000KO:K03350ncoils:Coil
OMA:SCCPANNPaxDb:Q8LGU6Pfam:PF00515Pfam:PF07719
Pfam:PF12895Pfam:PF13181Pfam:PF14559Pfam:Q8LGU6
Pfscan:PS50005Pfscan:PS50293PhylomeDB:Q8LGU6PIR:G84583
PRIDE:Q8LGU6PRO:PR:Q8LGU6PROSITE:PS50005PROSITE:PS50293
ProteinModelPortal:Q8LGU6Proteomes:UP000006548Reactome:R-ATH-174184Reactome:R-ATH-179409
RefSeq:NP_849994.1SMART:SM00028SMR:Q8LGU6STRING:3702.AT2G20000.1
SUPFAM:SSF48452TAIR:AT2G20000tair10-symbols:CDC27btair10-symbols:HBT
UniGene:At.39758UniPathway:UPA00143UniProt:Q8LGU6
Coordinates (TAIR10) chr2:-:8632324..8636900
Molecular Weight (calculated) 83072.70 Da
IEP (calculated) 6.55
GRAVY (calculated) -0.36
Length 744 amino acids
Sequence (TAIR10)
(BLAST)
001: MEAMLVDCVN NSLRHFVYKN AIFMCERLCA EFPSEVNLQL LATSYLQNNQ AYSAYHLLKG TQMAQSRYLF ALSCFQMDLL NEAESALCPV NEPGAEIPNG
101: AAGHYLLGLI YKYTDRRKNA AQQFKQSLTI DPLLWAAYEE LCILGAAEEA TAVFGETAAL SIQKQYMQQL STSLGLNTYN EERNSTSTKN TSSEDYSPRQ
201: SKHTQSHGLK DISGNFHSHG VNGGVSNMSF YNTPSPVAAQ LSGIAPPPLF RNFQPAVANP NSLITDSSPK STVNSTLQAP RRKFVDEGKL RKISGRLFSD
301: SGPRRSSRLS ADSGANINSS VATVSGNVNN ASKYLGGSKL SSLALRSVTL RKGHSWANEN MDEGVRGEPF DDSRPNTAST TGSMASNDQE DETMSIGGIA
401: MSSQTITIGV SEILNLLRTL GEGCRLSYMY RCQEALDTYM KLPHKHYNTG WVLSQVGKAY FELIDYLEAE KAFRLARLAS PYCLEGMDIY STVLYHLKED
501: MKLSYLAQEL ISTDRLAPQS WCAMGNCYSL QKDHETALKN FLRAVQLNPR FAYAHTLCGH EYTTLEDFEN GMKSYQNALR VDTRHYNAWY GLGMIYLRQE
601: KLEFSEHHFR MAFLINPSSS VIMSYLGTSL HALKRSEEAL EIMEQAIVAD RKNPLPMYQK ANILVCLERL DEALEVLEEL KEYAPSESSV YALMGRIYKR
701: RNMHDKAMLH FGLALDMKPP ATDVAAIKAA MEKLHVPDEI DESP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)