AT2G18915.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.628 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : LOV KELCH protein 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a member of F-box proteins that includes two other proteins in Arabidopsis (ZTL and FKF1). These proteins contain a unique structure containing a PAS domain at their N-terminus, an F-box motif, and 6 kelch repeats at their C-terminus. Overexpression results in arrhythmic phenotypes for a number of circadian clock outputs in both constant light and constant darkness, long hypocotyls under multiple fluences of both red and blue light, and a loss of photoperiodic control of flowering time. Although this the expression of this gene itself is not regulated by circadian clock, it physically interacts with Dof transcription factors that are transcriptionally regulated by circadian rhythm. LKP2 interacts with Di19, CO/COL family proteins. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
LOV KELCH protein 2 (LKP2); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), Kelch repeat type 1 (InterPro:IPR006652), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), PAS fold (InterPro:IPR013767), PAS (InterPro:IPR000014), Kelch repeat type 2 (InterPro:IPR011498), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT5G57360.1); Has 9191 Blast hits to 6011 proteins in 849 species: Archae - 93; Bacteria - 2251; Metazoa - 2432; Fungi - 932; Plants - 2094; Viruses - 0; Other Eukaryotes - 1389 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:-:8194792..8197255 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 66354.30 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.95 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.09 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 611 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MQNQMEWDSD SDLSGGDEVA EDGWFGGDNG AIPFPVGSLP GTAPCGFVVS DALEPDNPII YVNTVFEIVT GYRAEEVIGR NCRFLQCRGP FTKRRHPMVD 101: STIVAKMRQC LENGIEFQGE LLNFRKDGSP LMNKLRLVPI REEDEITHFI GVLLFTDAKI DLGPSPDLSA KEIPRISRSF TSALPIGERN VSRGLCGIFE 201: LSDEVIAIKI LSQLTPGDIA SVGCVCRRLN ELTKNDDVWR MVCQNTWGTE ATRVLESVPG AKRIGWVRLA REFTTHEATA WRKFSVGGTV EPSRCNFSAC 301: AVGNRIVIFG GEGVNMQPMN DTFVLDLGSS SPEWKSVLVS SPPPGRWGHT LSCVNGSRLV VFGGYGSHGL LNDVFLLDLD ADPPSWREVS GLAPPIPRSW 401: HSSCTLDGTK LIVSGGCADS GALLSDTFLL DLSMDIPAWR EIPVPWTPPS RLGHTLTVYG DRKILMFGGL AKNGTLRFRS NDVYTMDLSE DEPSWRPVIG 501: YGSSLPGGMA APPPRLDHVA ISLPGGRILI FGGSVAGLDS ASQLYLLDPN EEKPAWRILN VQGGPPRFAW GHTTCVVGGT RLVVLGGQTG EEWMLNEAHE 601: LLLATSTTAS T |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)