AT2G02560.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.997 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : cullin-associated and neddylation dissociated | ||||||||||||
| Curator Summary (TAIR10) |
Arabidopsis thaliana homolog of human CAND1 (cullin-associated and neddylation-dissociated). Putative similarity to TBP-interacting protein TIP120. Ubiquitously expressed in plant tissues throughout development. T-DNA insertion mutant plants were completely sterile and resistant to sirtinol and auxin, but not to gibberellins or brassinolide. Displayed developmental phenotypes similar to those of axr1, namely, short petioles, downwardly curling leaves, shorter inflorescence. Required for SCF function and appears to modulate SCF complex cycling. Physically interacts with CUL1. | ||||||||||||
| Computational Description (TAIR10) |
cullin-associated and neddylation dissociated (CAND1); FUNCTIONS IN: binding; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, vegetative to reproductive phase transition of meristem; LOCATED IN: cell wall, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), TATA-binding protein interacting (TIP20) (InterPro:IPR013932); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:690345..697342 | ||||||||||||
| Molecular Weight (calculated) | 134629.00 Da | ||||||||||||
| IEP (calculated) | 5.98 | ||||||||||||
| GRAVY (calculated) | -0.00 | ||||||||||||
| Length | 1217 amino acids | ||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MANLQVSGIL EKMTGKDKDY RYMATSDLLN ELNKDSFKID LDLEVRLSSI ILQQLDDVAG DVSGLAVKCL APLVKKVGEE RIVEMTNKLC DKLLHGKDQH 0101: RDTASIALRT VVAQIAPTLA PSILVTLTPQ MIGGISGQGM SSGIKCECLE IMCDVVQKYG SLMTDDHEKL LNTLLLQLGC NQATVRKKTV TCIASLASSL 0201: SDDLLAKATV EVVKNLSNRN AKSEITRTNI QMIGALCRAV GYRFGTHLGN TVPVLINYCT SASENDEELR EYSLQALESF LLRCPRDISP YCDEILNLTL 0301: EYISYDPNFT DNMEEDTDNE TLEDEEDDES ANEYTDDEDA SWKVRRAAAK CLAGLIVSRS EMLTKVYQEA CPKLIDRFKE REENVKMDVF NTFIDLLRQT 0401: GNVTKGQTDT DESSPKWLLK QEVSKIVKSI NRQLREKSVK TKVGAFSVLR ELVVVLPDCL ADHIGSLVPG IERALNDKSS TSNLKIEALV FTKLVLASHA 0501: PPVFHPYIKA LSSPVLAAVG ERYYKVTAEA LRVCGELVRV VRPSTAGMGF DFKPFVHPIY NAIMSRLTNQ DQDQEVKECA ITCMGLVIST FGDQLRAELP 0601: SCLPVLVDRM GNEITRLTAV KAFSVIATSP LHINLSCVLD HLIAELTGFL RKANRVLRQA TLITMNTLVT AYGDKIGSEA YEVILVELSS LISVSDLHMT 0701: ALALELCCTL MTGKSCSENI SLAVRNKVLP QALTLVKSPL LQGQALLDLQ KFFEALVYHA NTSFYTLLES LLSCAKPSPQ SGGVPKQALY SIAQCVAVLC 0801: LAAGDKNCSS TVKMLMEILK DDSGTNSAKQ HLALLSLGEI GRRKDLSAHA GIETIVIESF QSPFEEIKSA ASYALGNIAV GNLSNYLPFI LDQIDNQQKK 0901: QYILLHSLKE VIVRQSVDKA DFQNSSVEKI LALLFNHCES EEEGVRNVVA ECLGKMALIE PEKLVPALQV RTTSPAAFTR ATVVTAVKYS VVERPEKLDE 1001: IIFPQISSFL MLIKDGDRHV RRAAVSALST FAHYKPNLIK GLLPELLPLL YDQTVIKKEL IRTVDLGPFK HVVDDGLELR KAAFECVFTL VDSCLDQVNP 1101: SSFIVPFLKS GLEDHYDLKM LCHLILSLLA DKCPSAVLAV LDSLVEPLHK TISFKPKQDA VKQEHDRNED MIRSALRAIS SLDRINGVDY SHKFKGLMGD 1201: MKRSVPLWEK FQTIRNE |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)