AT1G77300.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : histone methyltransferases(H3-K4 specific);histone methyltransferases(H3-K36 specific) | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein with histone lysine N-methyltransferase activity required specifically for the trimethylation of H3-K4 in FLC chromatin (and not in H3-K36 dimethylation). Acts as an inhibitor of flowering specifically involved in the autonomous promotion pathway. EFS also regulates the expression of genes involved in carotenoid biosynthesis.Modification of histone methylation at the CRTISO locus reduces transcript levels 90%. The increased shoot branching seen in some EFS mutants is likely due to the carotenoid biosynthesis defect having an effect on stringolactones.Required for ovule, embryo sac, anther and pollen development. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
EARLY FLOWERING IN SHORT DAYS (EFS); FUNCTIONS IN: histone methyltransferase activity (H3-K4 specific); INVOLVED IN: in 10 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Post-SET domain (InterPro:IPR003616), AWS (InterPro:IPR006560), Zinc finger, CW-type (InterPro:IPR011124); BEST Arabidopsis thaliana protein match is: SET domain group 26 (TAIR:AT1G76710.2); Has 6227 Blast hits to 6009 proteins in 532 species: Archae - 3; Bacteria - 662; Metazoa - 2557; Fungi - 556; Plants - 1120; Viruses - 3; Other Eukaryotes - 1326 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:29040936..29048810 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 164326.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.94 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.72 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1501 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MDCKENGVGD ASGCNIDANS LASNLAMNTN EDFYEKLSSR GQNLDSVSSL EIPQTASSVN HTIEGQRKCF TEIEQMGYGN SNSQEDAGNT DDDLYVCYNA 0101: DDTQEQGVVS GELEQSQELI CDTDLLVNCN KLDDGKESQD TNVSLVSIFS GSMQEKEAPQ AKEDEGYGGT TLPIGGSGID TESTFVNDAP EQFESLETTK 0201: HIKPDEVESD GISYRFDDGG KEGRNGPSSD LDTGSSDDIS LSQSFSFPDS LLDSSVFGCS ATESYLEDAI DIEGNGTIVV SPSLAITEML NNDDGGLCSH 0301: DLNKITVTET INPDLKLVRE DRLDTDLSVM NEKMLKNHVG DSSSESAVAA LSMNNGMAAD LRAENFSQSS PIDEKTLDME ANSPITDSSL IWNFPLNFGS 0401: GGIEVCNPEN AVEPLRIVDD NGRIGGEVAS ASGSDFCEAG MSSSRRKARD GKQCKVVQTK TSARHLRKSS RKKQSERDIE SIFKCSKQKR SSLLKTSRSS 0501: EWGLPSKTTE IFLQSNNIPY DGPPHHEPQR SQGNLNNGEH NRSSHNGNVE GSNRNIQASS GSCLRLKVKF GKSGGQNPLN ITVSKVSGNS LPGNGIVKAG 0601: TCLELPGSAH FGEDKMQTVE TKEDLVEKSN PVEKVSYLQS SDSMRDKKYN QDAGGLCRKV GGDVLDDDPH LSSIRMVEEC ERATGTQSLD AETSPDSEVI 0701: NSVPDSIVNI EHKEGLHHGF FSTPEDVVKK NRVLEKEDEL RASKSPSENG SHLIPNAKKA KHPKSKSNGT KKGKSKFSES AKDGRKNESH EGVEQRKSLN 0801: TSMGRDDSDY PEVGRIESHK TTGALLDADI GKTSATYGTI SSDVTHGEMV VDVTIEDSYS TESAWVRCDD CFKWRRIPAS VVGSIDESSR WICMNNSDKR 0901: FADCSKSQEM SNEEINEELG IGQDEADAYD CDAAKRGKEK EQKSKRLTGK QKACFKAIKT NQFLHRNRKS QTIDEIMVCH CKPSPDGRLG CGEECLNRML 1001: NIECLQGTCP AGDLCSNQQF QKRKYVKFER FQSGKKGYGL RLLEDVREGQ FLIEYVGEVL DMQSYETRQK EYAFKGQKHF YFMTLNGNEV IDAGAKGNLG 1101: RFINHSCEPN CRTEKWMVNG EICVGIFSMQ DLKKGQELTF DYNYVRVFGA AAKKCYCGSS HCRGYIGGDP LNGDVIIQSD SDEEYPELVI LDDDESGEGI 1201: LGATSRTFTD DADEQMPQSF EKVNGYKDLA PDNTQTQSSV SVKLPEREIP PPLLQPTEVL KELSSGISIT AVQQEVPAEK KTKSTSPTSS SLSRMSPGGT 1301: NSDKTTKHGS GEDKKILPRP RPRMKTSRSS ESSKRDKGGI YPGVNKAQVI PVNKLQQQPI KSKGSEKVSP SIETFEGKLN ELLDAVGGIS KRRDSAKGYL 1401: KLLLLTAASR GTDEEGIYSN RDLSMILDAL LKTKSKSVLV DIINKNGLLL QGWKALRTLF YHSPSMTTIR FIILRGASET DGYLSILENL GASTGRRDRS 1501: L |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)