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AT1G68760.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : nudix hydrolase 1
Curator
Summary (TAIR10)
Encodes a cytosol-localized nudix hydrolase that hydrolyzes 8-oxo-(d)GTP to its monophosphate form. This protective mechanism prevents the misincorporation of these oxidized nucleotides into DNA and RNA. NUDX1 also has a low level of dihydroneopterin triphosphate pyrophosphatase activity in vitro and may participate in the folate synthesis pathway.
Computational
Description (TAIR10)
nudix hydrolase 1 (NUDX1); FUNCTIONS IN: hydrolase activity, dihydroneopterin triphosphate pyrophosphohydrolase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; INVOLVED IN: response to DNA damage stimulus; LOCATED IN: cytosol; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase (InterPro:IPR020476), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); Has 6319 Blast hits to 6317 proteins in 1575 species: Archae - 191; Bacteria - 5327; Metazoa - 193; Fungi - 66; Plants - 51; Viruses - 14; Other Eukaryotes - 477 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G68760-MONOMERBioCyc:MetaCyc:AT1G68760-MONOMERBRENDA:3.6.1.B15EC:3.6.1.22
EC:3.6.1.55EC:3.6.1.67eggNOG:COG1051eggNOG:ENOG410J0G8
EMBL:AC011914EMBL:AK117564EMBL:AK176885EMBL:AY088162
EMBL:BT005039EMBL:CP002684EnsemblPlants:AT1G68760EnsemblPlants:AT1G68760.1
entrez:843207Gene3D:3.90.79.10GeneID:843207Genevisible:Q9CA40
GO:GO:0000210GO:GO:0005829GO:GO:0006203GO:GO:0006974
GO:GO:0008413GO:GO:0019177GO:GO:0035539GO:GO:0046872
Gramene:AT1G68760.1gramene_pathway:3.6.1.-gramene_pathway:PWY-3742gramene_pathway:PWY-6502
hmmpanther:PTHR16099hmmpanther:PTHR16099:SF5HOGENOM:HOG000261967InParanoid:Q9CA40
InterPro:IPR000086InterPro:IPR015797InterPro:IPR020084InterPro:IPR020476
iPTMnet:Q9CA40KEGG:ath:AT1G68760KO:K03574OMA:IMEPEKC
PaxDb:Q9CA40Pfam:PF00293Pfam:Q9CA40Pfscan:PS51462
PhylomeDB:Q9CA40PIR:D96712PRIDE:Q9CA40PRINTS:PR00502
PRO:PR:Q9CA40PROSITE:PS00893PROSITE:PS51462ProteinModelPortal:Q9CA40
Proteomes:UP000006548Reactome:R-ATH-2393930RefSeq:NP_177044.1SABIO-RK:Q9CA40
scanprosite:PS00893SMR:Q9CA40STRING:3702.AT1G68760.1SUPFAM:SSF55811
TAIR:AT1G68760tair10-symbols:ATNUDT1tair10-symbols:ATNUDX1tair10-symbols:NUDX1
UniGene:At.35484UniProt:Q9CA40
Coordinates (TAIR10) chr1:+:25829090..25829607
Molecular Weight (calculated) 16357.50 Da
IEP (calculated) 4.82
GRAVY (calculated) -0.27
Length 147 amino acids
Sequence (TAIR10)
(BLAST)
001: MSTGEAIPRV AVVVFILNGN SILLGRRRSS IGNSTFALPG GHLEFGESFE ECAAREVMEE TGLKIEKMKL LTVTNNVFKE APTPSHYVSV SIRAVLVDPS
101: QEPKNMEPEK CEGWDWYDWE NLPKPLFWPL EKLFGSGFNP FTHGGGD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)