suba logo
AT1G61560.4
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of cotyledons, young leaves and petals, in mature rosette leaves, in anthers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 6 (MLO6); CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G11310.1).
Protein Annotations
eggNOG:ENOG410IHFAeggNOG:ENOG410ZUVBEMBL:CP002684EnsemblPlants:AT1G61560
EnsemblPlants:AT1G61560.4entrez:842450ExpressionAtlas:F4HVC5GeneID:842450
GO:GO:0006952GO:GO:0009607GO:GO:0016021Gramene:AT1G61560.4
hmmpanther:PTHR31942hmmpanther:PTHR31942:SF29InterPro:IPR004326PaxDb:F4HVC5
Pfam:PF03094PRIDE:F4HVC5Proteomes:UP000006548RefSeq:NP_001185282.1
STRING:3702.AT1G61560.1TAIR:AT1G61560tair10-symbols:MLO6TMHMM:TMhelix
UniGene:At.11096UniProt:F4HVC5
Coordinates (TAIR10) chr1:-:22708875..22711488
Molecular Weight (calculated) 60000.70 Da
IEP (calculated) 10.04
GRAVY (calculated) -0.15
Length 521 amino acids
Sequence (TAIR10)
(BLAST)
001: MLMGFISLLL TIGQGYISNI CIPKNIAASM HPCSASEEAR KYGKKDVPKE DEEENLRRKL LQLVDSLIPR RSLATKGYDK CAEKGKVAFV SAYGMHQLHI
101: FIFVLAVCHV IYCIVTYALG KTKMRRWKKW EEETKTIEYQ YSHDPERFRF ARDTSFGRRH LSFWSKSTIT LWIVCFFRQF FRSVTKVDYL TLRHGFIMAH
201: LAPGSDARFD FRKYIQRSLE EDFKTIVEIN PVIWFIAVLF LLTNTNGLNS YLWLPFIPFI VILIVGTKLQ VIITKLGLRI QEKGDVVKGT PLVQPGDHFF
301: WFGRPRFILF LIHLVLFTNA FQLAFFVWST VSKQSCILHE LETVDVIIRI SIGLLVQILC SYVTLPLYAL VTQMGSKMKP TVFNERVATA LKSWHHTAKK
401: NIKHGRTSES TTPFSSRPTT PTHGSSPIHL LRNAPHKRSR SVDESFANSF SPRNSDFDSW DPESQHETAE TSNSNHRSRF GEEESEKKFV SSSVELPPGP
501: GQIRTQHEIS TISLRDFSFK R
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)