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AT1G59750.4
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : auxin response factor 1
Curator
Summary (TAIR10)
Encodes a member of the auxin response factor family. ARFs bind to the cis element 5'-TGTCTC-3' ARFs mediate changes in gene expression in response to auxin. ARF's form heterodimers with IAA/AUX genes. ARF1 enhances mutant phenotypes of ARF2 and may act with ARF2 to control aspects of maturation and senescence.ARF1:LUC and 3xHA:ARF1 proteins have a half-life of ~3-4 hours and their degradation is reduced by proteasome inhibitors. 3xHA:ARF1 degradation is not affected by a pre-treatment with IAA. A nuclear-targeted fusion protein containing the middle region of ARF1 linked to LUC:NLS has a similar half-life to the full-length ARF1:LUC construct. The degradation of 3xHA:ARF1 is not affected in an axr6-3 mutant grown at room temperature, although the degradation of AXR2/IAA7 is slowed under these conditions.
Computational
Description (TAIR10)
auxin response factor 1 (ARF1); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), Transcriptional factor B3 (InterPro:IPR003340), AUX/IAA protein (InterPro:IPR003311), Auxin response factor (InterPro:IPR010525); BEST Arabidopsis thaliana protein match is: auxin response factor 11 (TAIR:AT2G46530.3).
Protein Annotations
eggNOG:ENOG410IHVYeggNOG:ENOG410Y8ZKEMBL:CP002684EnsemblPlants:AT1G59750
EnsemblPlants:AT1G59750.4entrez:842268ExpressionAtlas:F4ID31Gene3D:2.40.330.10
GeneID:842268GO:GO:0003677GO:GO:0005634GO:GO:0006351
GO:GO:0006355GO:GO:0009734Gramene:AT1G59750.4hmmpanther:PTHR31384
hmmpanther:PTHR31384:SF28InterPro:IPR000270InterPro:IPR003340InterPro:IPR010525
InterPro:IPR015300InterPro:IPR033389PaxDb:F4ID31Pfam:PF02309
Pfam:PF02362Pfam:PF06507Pfscan:PS50863Pfscan:PS51745
PROSITE:PS50863PROSITE:PS51745ProteinModelPortal:F4ID31Proteomes:UP000006548
RefSeq:NP_001185266.1SMART:SM01019SMR:F4ID31STRING:3702.AT1G59750.1
SUPFAM:SSF101936SUPFAM:SSF54277TAIR:AT1G59750tair10-symbols:ARF1
UniGene:At.74832UniProt:F4ID31
Coordinates (TAIR10) chr1:+:21980414..21984193
Molecular Weight (calculated) 73219.90 Da
IEP (calculated) 6.15
GRAVY (calculated) -0.57
Length 660 amino acids
Sequence (TAIR10)
(BLAST)
001: MAASNHSSGK PGGVLSDALC RELWHACAGP LVTLPREGER VYYFPEGHME QLEASMHQGL EQQMPSFNLP SKILCKVINI QRRAEPETDE VYAQITLLPE
101: LDQSEPTSPD APVQEPEKCT VHSFCKTLTA SDTSTHGGFS VLRRHADDCL PPLDMSQQPP WQELVATDLH NSEWHFRHIF RGQPRRHLLT TGWSVFVSSK
201: KLVAGDAFIF LRGENEELRV GVRRHMRQQT NIPSSVISSH SMHIGVLATA AHAITTGTIF SVFYKPRTSR SEFIVSVNRY LEAKTQKLSV GMRFKMRFEG
301: EEAPEKRFSG TIVGVQENKS SVWHDSEWRS LKVQWDEPSS VFRPERVSPW ELEPLVANST PSSQPQPPQR NKRPRPPGLP SPATGPSDGV WKSPADTPSS
401: VPLFSPPAKA ATFGHGGNKS FGVSIGSAFW PTNADSAAES FASAFNNEST EKKQTNGNVC RLFGFELVEN VNVDECFSAA SVSGAVAVDQ PVPSNEFDSG
501: QQSEPLNINQ SDIPSGSGDP EKSSLRSPQE SQSRQIRSCT KVHMQGSAVG RAIDLTRSEC YEDLFKKLEE MFDIKGELLE STKKWQVVYT DDEDDMMMVG
601: DDPWNEFCGM VRKIFIYTPE EVKKLSPKNK LAVNARMQLK ADAEENGNTE GRSSSMAGSR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)