AT1G59750.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : auxin response factor 1 | ||||||||||||
| Curator Summary (TAIR10) |
Encodes a member of the auxin response factor family. ARFs bind to the cis element 5'-TGTCTC-3' ARFs mediate changes in gene expression in response to auxin. ARF's form heterodimers with IAA/AUX genes. ARF1 enhances mutant phenotypes of ARF2 and may act with ARF2 to control aspects of maturation and senescence.ARF1:LUC and 3xHA:ARF1 proteins have a half-life of ~3-4 hours and their degradation is reduced by proteasome inhibitors. 3xHA:ARF1 degradation is not affected by a pre-treatment with IAA. A nuclear-targeted fusion protein containing the middle region of ARF1 linked to LUC:NLS has a similar half-life to the full-length ARF1:LUC construct. The degradation of 3xHA:ARF1 is not affected in an axr6-3 mutant grown at room temperature, although the degradation of AXR2/IAA7 is slowed under these conditions. | ||||||||||||
| Computational Description (TAIR10) |
auxin response factor 1 (ARF1); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), Transcriptional factor B3 (InterPro:IPR003340), AUX/IAA protein (InterPro:IPR003311), Auxin response factor (InterPro:IPR010525); BEST Arabidopsis thaliana protein match is: auxin response factor 11 (TAIR:AT2G46530.3); Has 2481 Blast hits to 2103 proteins in 109 species: Archae - 0; Bacteria - 12; Metazoa - 22; Fungi - 4; Plants - 2392; Viruses - 0; Other Eukaryotes - 51 (source: NCBI BLink). | ||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:21980414..21984193 | ||||||||||||
| Molecular Weight (calculated) | 73374.10 Da | ||||||||||||
| IEP (calculated) | 6.15 | ||||||||||||
| GRAVY (calculated) | -0.57 | ||||||||||||
| Length | 662 amino acids | ||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAASNHSSGK PGGVLSDALC RELWHACAGP LVTLPREGER VYYFPEGHME QLEASMHQGL EQQMPSFNLP SKILCKVINI QRRAEPETDE VYAQITLLPE 101: LDQSEPTSPD APVQEPEKCT VHSFCKTLTA SDTSTHGGFS VLRRHADDCL PPLDMSQQPP WQELVATDLH NSEWHFRHIF RGQPRRHLLT TGWSVFVSSK 201: KLVAGDAFIF LRGENEELRV GVRRHMRQQT NIPSSVISSH SMHIGVLATA AHAITTGTIF SVFYKPRTSR SEFIVSVNRY LEAKTQKLSV GMRFKMRFEG 301: EEAPEKRFSG TIVGVQENKS SVWHDSEWRS LKVQWDEPSS VFRPERVSPW ELEPLVANST PSSQPQPPQR NKRPRPPGLP SPATGPSGPD GVWKSPADTP 401: SSVPLFSPPA KAATFGHGGN KSFGVSIGSA FWPTNADSAA ESFASAFNNE STEKKQTNGN VCRLFGFELV ENVNVDECFS AASVSGAVAV DQPVPSNEFD 501: SGQQSEPLNI NQSDIPSGSG DPEKSSLRSP QESQSRQIRS CTKVHMQGSA VGRAIDLTRS ECYEDLFKKL EEMFDIKGEL LESTKKWQVV YTDDEDDMMM 601: VGDDPWNEFC GMVRKIFIYT PEEVKKLSPK NKLAVNARMQ LKADAEENGN TEGRSSSMAG SR |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)