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AT1G50430.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.680
What is SUBAcon?
Predictors External Curations
SwissProt : endoplasmic reticulum 16381842
TAIR : plasma membrane 17317660
TAIR : endoplasmic reticulum 8631902
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Ergosterol biosynthesis ERG4/ERG24 family
Curator
Summary (TAIR10)
Mutants are defective in Brassinosteroid biosynthesis (delta7-sterol-C7 reduction step) and have a dwarf phenotype.
Computational
Description (TAIR10)
DWARF 5 (DWF5); FUNCTIONS IN: sterol delta7 reductase activity; INVOLVED IN: sterol biosynthetic process, unidimensional cell growth, brassinosteroid biosynthetic process; LOCATED IN: integral to endoplasmic reticulum membrane, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sterol reductase, conserved site (InterPro:IPR018083), Ergosterol biosynthesis ERG4/ERG24 (InterPro:IPR001171); BEST Arabidopsis thaliana protein match is: Ergosterol biosynthesis ERG4/ERG24 family (TAIR:AT3G52940.1); Has 974 Blast hits to 971 proteins in 205 species: Archae - 0; Bacteria - 51; Metazoa - 266; Fungi - 402; Plants - 150; Viruses - 3; Other Eukaryotes - 102 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XP67eggNOG:KOG1435EMBL:CP002684EnsemblPlants:AT1G50430
EnsemblPlants:AT1G50430.2entrez:841465ExpressionAtlas:A8MS34GeneID:841465
GO:GO:0016021GO:GO:0016628Gramene:AT1G50430.2gramene_pathway:1.3.1.21
gramene_pathway:PWY-2541gramene_pathway:PWY-6663gramene_plant_reactome:1119370gramene_plant_reactome:6876419
hmmpanther:PTHR21257hmmpanther:PTHR21257:SF34HOGENOM:HOG000193296InterPro:IPR001171
InterPro:IPR018083KEGG:ath:AT1G50430KO:K00213PaxDb:A8MS34
Pfam:PF01222PRIDE:A8MS34PROSITE:PS01017PROSITE:PS01018
ProteinModelPortal:A8MS34Proteomes:UP000006548RefSeq:NP_001077693.1scanprosite:PS01017
scanprosite:PS01018SMR:A8MS34STRING:3702.AT1G50430.1TAIR:AT1G50430
tair10-symbols:7REDtair10-symbols:DWF5tair10-symbols:LEtair10-symbols:PA
tair10-symbols:ST7RTMHMM:TMhelixUniGene:At.25165UniProt:A8MS34
Coordinates (TAIR10) chr1:-:18682175..18685555
Molecular Weight (calculated) 49407.40 Da
IEP (calculated) 8.43
GRAVY (calculated) 0.37
Length 431 amino acids
Sequence (TAIR10)
(BLAST)
001: MAETVHSPIV TYASMLSLLA FCPPFVILLW YTMVHQDGSV TQTFGFFWEN GVQGLINIWP RPTLIAWKII FCYGAFEAIL QLLLPGKRVE GPISPAGNRP
101: VYKANGLAAY FVTLATYLGL WFGIFNPAIV YDHLGEIFSA LIFGSFIFCV LLYIKGHVAP SSSDSGSCGN LIIDFYWGME LYPRIGKSFD IKVFTNCRFG
201: MMSWAVLAVT YCIKQYEING KVSDSMLVNT ILMLVYVTKF FWWEAGYWNT MDIAHDRAGF YICWGCLVWV PSVYTSPGMY LVNHPVELGT QLAIYILVAG
301: ILCIYINYDC DRQRQEFRRT NGKCLVWGRA PSKIVASYTT TSGETKTSLL LTSGWWGLAR HFHYVPEILS AFFWTVPALF DNFLAYFYVI FLTLLLFDRA
401: KRDDDRCRSK YGKYWKLYCE KVKYRIIPGI Y
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)