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AT1G26700.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO14 belongs to the clade I, with AtMLO4 and AtMLO11. The gene is expressed during early seedling growth, in developing primary root, and particularly in root tips of 10-day old seedlings; it was not expressed in leaves or flowers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 14 (MLO14); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, LP.10 ten leaves visible, F mature embryo stage, 4 leaf senescence stage, LP.08 eight leaves visible; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G53760.2); Has 532 Blast hits to 521 proteins in 52 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 523; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).
Protein Annotations
BioGrid:24447eggNOG:ENOG410IK25eggNOG:ENOG410XR5SEMBL:AC006535
EMBL:AF369575EMBL:CP002684EnsemblPlants:AT1G26700EnsemblPlants:AT1G26700.1
entrez:839211GeneID:839211Genevisible:Q94KB1GO:GO:0005886
GO:GO:0006952GO:GO:0009607GO:GO:0016021Gramene:AT1G26700.1
hmmpanther:PTHR31942hmmpanther:PTHR31942:SF15HOGENOM:HOG000239166InParanoid:Q94KB1
InterPro:IPR004326KEGG:ath:AT1G26700KO:K08472OMA:TEPSERT
PaxDb:Q94KB1Pfam:PF03094Pfam:Q94KB1PhylomeDB:Q94KB1
PIR:H86393PRIDE:Q94KB1PRO:PR:Q94KB1Proteomes:UP000006548
RefSeq:NP_564257.1STRING:3702.AT1G26700.1TAIR:AT1G26700tair10-symbols:ATMLO14
tair10-symbols:MLO14TMHMM:TMhelixUniGene:At.19092UniProt:Q94KB1
Coordinates (TAIR10) chr1:+:9228300..9232237
Molecular Weight (calculated) 63926.60 Da
IEP (calculated) 8.59
GRAVY (calculated) 0.02
Length 554 amino acids
Sequence (TAIR10)
(BLAST)
001: MREETEPSER TLGLTPTWSV ATVLTIFVFV SLIVERSIHR LSNWLQKTKR KPLFAALEKM KEELMLLGFI SLLLTATSST IANICVSSSF HNDRFVPCTP
101: SEINEELEST ISTVKRTQLT RSLFLHTLRR RLSGIGEDTC SEGHEPFLSY EGMEQLHRFI FIMAVTHVTY SCLTMLLAIV KIHRWRIWED EVHMDRNDCL
201: TVVAREKIFR RQTTFVQYHT SAPLVKNRLL IWVICFFRQF GHSVVRSDYL TLRKGFIMNH HLTLTYDFHS YMIRSMEEEF QKIVGVSGPL WGFVVGFMLF
301: NIKGSNLYFW LAIIPITLVL LVGAKLQHVI ATLALENASI TEYASGIKLR PRDELFWFKK PELLLSLIHF IQFQNAFELA SFFWFWWQFG YNSCFLRNHL
401: LVYLRLILGF SGQFLCSYST LPLYALVTQM GTNYKAALLP QRVRETINGW GKATRRKRRH GLYGDDSTIR TETSTIASVD EYNDQVLDVS ETSPVQDNEL
501: ELQLIRGACG NSSSVETPIL RPCASISSTT FSRLQTETTD SLSRSSSLPM RREC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)