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AT1G24470.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:19439572 (2009): endoplasmic reticulum
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : beta-ketoacyl reductase 2
Curator
Summary (TAIR10)
Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene.
Computational
Description (TAIR10)
beta-ketoacyl reductase 2 (KCR2); FUNCTIONS IN: oxidoreductase activity, ketoreductase activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: beta-ketoacyl reductase 1 (TAIR:AT1G67730.1); Has 80088 Blast hits to 80001 proteins in 3265 species: Archae - 726; Bacteria - 55481; Metazoa - 4714; Fungi - 3206; Plants - 2039; Viruses - 0; Other Eukaryotes - 13922 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G24470-MONOMEREC:1.-.-.-eggNOG:COG0300eggNOG:ENOG410IJ2F
EMBL:AC000103EMBL:BT030066EMBL:CP002684EnsemblPlants:AT1G24470
EnsemblPlants:AT1G24470.1entrez:839063Gene3D:3.40.50.720GeneID:839063
Genevisible:Q9FYL6GO:GO:0005783GO:GO:0005789GO:GO:0016021
GO:GO:0045703Gramene:AT1G24470.1hmmpanther:PTHR24322hmmpanther:PTHR24322:SF552
HOGENOM:HOG000039237InParanoid:Q9FYL6InterPro:IPR002347InterPro:IPR016040
InterPro:IPR020904KEGG:ath:AT1G24470OMA:FWAHSLQPANTHER:PTHR24322
PaxDb:Q9FYL6Pfam:PF00106Pfam:Q9FYL6PhylomeDB:Q9FYL6
PIRSF:PIRSF000126PRIDE:Q9FYL6PRINTS:PR00080PRINTS:PR00081
PRO:PR:Q9FYL6PROSITE:PS00061ProteinModelPortal:Q9FYL6Proteomes:UP000006548
Reactome:R-ATH-193048Reactome:R-ATH-75876RefSeq:NP_173856.1scanprosite:PS00061
SMR:Q9FYL6STRING:3702.AT1G24470.1SUPFAM:SSF51735TAIR:AT1G24470
tair10-symbols:ATKCR2tair10-symbols:KCR2TMHMM:TMhelixUniGene:At.49913
UniGene:At.66963UniProt:Q9FYL6
Coordinates (TAIR10) chr1:+:8674056..8676277
Molecular Weight (calculated) 35013.90 Da
IEP (calculated) 9.76
GRAVY (calculated) 0.26
Length 312 amino acids
Sequence (TAIR10)
(BLAST)
001: MQGACISESQ PWYLHFVCFI GFLFLLRVLF IPLLKWFTTR FLLTPKRLKR YGSWAMVTGA TEGIGRAFAH ELAKHGLNLI LVSRNLSKLE SVSDDFQQEF
101: PHIKIKIIPF DFSSEGGYGA IEEGIKGLEV GILINNVGIT YPRAMFFHEV DQLTWTKILR VNLEATTWVT RSLIGPMLHR RRGAIVNISS GAAVVVPSHP
201: LYAIYAATKA YVDALSRSLH VEYKQFGIDV QCQVPLYVST RMVSEVAAID KPSLFVPSPE VYAKAAVAQI GIGSRCSPFW AHSLQWFLVG LVPDNLVDTW
301: RLSIGLRRRS LS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)