AT1G24470.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:endoplasmic reticulum 1.000 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : beta-ketoacyl reductase 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
beta-ketoacyl reductase 2 (KCR2); FUNCTIONS IN: oxidoreductase activity, ketoreductase activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: beta-ketoacyl reductase 1 (TAIR:AT1G67730.1); Has 80088 Blast hits to 80001 proteins in 3265 species: Archae - 726; Bacteria - 55481; Metazoa - 4714; Fungi - 3206; Plants - 2039; Viruses - 0; Other Eukaryotes - 13922 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr1:+:8674056..8676277 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 35013.90 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 9.76 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | 0.26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 312 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MQGACISESQ PWYLHFVCFI GFLFLLRVLF IPLLKWFTTR FLLTPKRLKR YGSWAMVTGA TEGIGRAFAH ELAKHGLNLI LVSRNLSKLE SVSDDFQQEF 101: PHIKIKIIPF DFSSEGGYGA IEEGIKGLEV GILINNVGIT YPRAMFFHEV DQLTWTKILR VNLEATTWVT RSLIGPMLHR RRGAIVNISS GAAVVVPSHP 201: LYAIYAATKA YVDALSRSLH VEYKQFGIDV QCQVPLYVST RMVSEVAAID KPSLFVPSPE VYAKAAVAQI GIGSRCSPFW AHSLQWFLVG LVPDNLVDTW 301: RLSIGLRRRS LS |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)