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AT1G21750.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 0.735
What is SUBAcon?
Predictors External Curations
SwissProt : endoplasmic reticulum 16381842
TAIR : plastid 15028209
TAIR : vacuole 18676877
TAIR : endoplasmic reticulum 16618929
TAIR : vacuole 15539469
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : PDI-like 1-1
Curator
Summary (TAIR10)
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily; isoform contains non-consensus GA donor splice site at intron 9. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). Neither AtIRE1-2 nor AtbZIP60 appear to be required for this response.
Computational
Description (TAIR10)
PDI-like 1-1 (PDIL1-1); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: in 6 processes; LOCATED IN: in 8 components; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Protein disulphide isomerase (InterPro:IPR005792), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 1-2 (TAIR:AT1G77510.1); Has 30765 Blast hits to 17459 proteins in 2902 species: Archae - 337; Bacteria - 14753; Metazoa - 5498; Fungi - 1629; Plants - 2433; Viruses - 29; Other Eukaryotes - 6086 (source: NCBI BLink).
Protein Annotations
EC:5.3.4.1eggNOG:COG0526eggNOG:KOG0190EMBL:CP002684
EnsemblPlants:AT1G21750EnsemblPlants:AT1G21750.2entrez:838779ExpressionAtlas:F4HZN9
Gene3D:3.40.30.10GeneID:838779GO:GO:0003756GO:GO:0005783
GO:GO:0045454Gramene:AT1G21750.2hmmpanther:PTHR18929hmmpanther:PTHR18929:SF108
InterPro:IPR005788InterPro:IPR005792InterPro:IPR012336InterPro:IPR013766
InterPro:IPR017937PaxDb:F4HZN9Pfam:PF00085Pfam:PF13848
Pfscan:PS51352PRIDE:F4HZN9PROSITE:PS00194PROSITE:PS51352
ProteinModelPortal:F4HZN9Proteomes:UP000006548RefSeq:NP_849696.1scanprosite:PS00194
SMR:F4HZN9STRING:3702.AT1G21750.1SUPFAM:SSF52833TAIR:AT1G21750
tair10-symbols:ATPDIL1-1tair10-symbols:PDIL1-1TIGRfam:TIGR01126TIGRfam:TIGR01130
TIGRFAMs:TIGR01126TIGRFAMs:TIGR01130UniGene:At.24814UniProt:F4HZN9
Coordinates (TAIR10) chr1:+:7645767..7648695
Molecular Weight (calculated) 54161.80 Da
IEP (calculated) 4.72
GRAVY (calculated) -0.25
Length 487 amino acids
Sequence (TAIR10)
(BLAST)
001: MAMRGFTLFS ILVLSLCASS IRSEETETKE FVLTLDHTNF TDTINKHDFI VVEFYAPWCG HCKQLAPEYE KAASALSSNV PPVVLAKIDA SEETNREFAT
101: QYEVQGFPTI KIFRNGGKAV QEYNGPREAE GIVTYLKKQS GPASAEIKSA DDASEVVSDK KVVVVGIFPK LSGSEFDSFM AIAEKLRSEL DFAHTSDAKL
201: LPRGESSVTG PVVRLFKPFD EQFVDSKDFD GEALEKFVKE SSIPLITVFD KDPNNHPYVI KFFESTNTKA MLFINFTGEG AESLKSKYRE VATSNKGQGL
301: SFLLGDAENS QGAFQYFGLE ESQVPLIIIQ TADDKKYLKT NVEVDQIESW VKDFKDGKIA PHKKSQPIPA ENNEPVKVVV SDSLDDIVLN SGKNVLLEFY
401: APWCGHCQKL APILDEVAVS YQSDSSVVIA KLDATANDFP KDTFDVKGFP TIYFKSASGN VVVYEGDRQR ESLYLFIRFL YVHSSEQ
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)