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AT1G19350.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Brassinosteroid signalling positive regulator (BZR1) family protein
Curator
Summary (TAIR10)
Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes
Computational
Description (TAIR10)
BRI1-EMS-SUPPRESSOR 1 (BES1); CONTAINS InterPro DOMAIN/s: BZR1, transcriptional repressor (InterPro:IPR008540); BEST Arabidopsis thaliana protein match is: Brassinosteroid signalling positive regulator (BZR1) family protein (TAIR:AT1G75080.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IGXVeggNOG:ENOG410YC62EMBL:CP002684EnsemblPlants:AT1G19350
EnsemblPlants:AT1G19350.3entrez:838518ExpressionAtlas:F4HP45GeneID:838518
GO:GO:0001046GO:GO:0003677GO:GO:0003700GO:GO:0005634
GO:GO:0005829GO:GO:0006355GO:GO:0009742GO:GO:0042742
GO:GO:0045892Gramene:AT1G19350.3hmmpanther:PTHR31506hmmpanther:PTHR31506:SF6
InterPro:IPR008540InterPro:IPR033264OMA:LPTWESFPANTHER:PTHR31506
PaxDb:F4HP45Pfam:PF05687PRIDE:F4HP45ProteinModelPortal:F4HP45
Proteomes:UP000006548RefSeq:NP_973863.1STRING:3702.AT1G19350.3TAIR:AT1G19350
tair10-symbols:BES1tair10-symbols:BZR2UniGene:At.24276UniProt:F4HP45
Coordinates (TAIR10) chr1:+:6688680..6690165
Molecular Weight (calculated) 39241.70 Da
IEP (calculated) 10.03
GRAVY (calculated) -0.75
Length 357 amino acids
Sequence (TAIR10)
(BLAST)
001: MKRFFYNSSE EERKKKAYSS KKMTSDGATS TSAAAAAAAM ATRRKPSWRE RENNRRRERR RRAVAAKIYT GLRAQGNYNL PKHCDNNEVL KALCSEAGWV
101: VEEDGTTYRK GHKPLPGDMA GSSSRATPYS SHNQSPLSST FDSPILSYQV SPSSSSFPSP SRVGDPHNIS TIFPFLRNGG IPSSLPPLRI SNSAPVTPPV
201: SSPTSRNPKP LPTWESFTKQ SMSMAAKQSM TSLNYPFYAV SAPASPTHHR QFHAPATIPE CDESDSSTVD SGHWISFQKF AQQQPFSASM VPTSPTFNLV
301: KPAPQQLSPN TAAIQEIGQS SEFKFENSQV KPWEGERIHD VAMEDLELTL GNGKAHS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)