AT1G15750.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.985 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Transducin family protein / WD-40 repeat family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:5415086..5420359 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 124305.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.25 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.30 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1131 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MSSLSRELVF LILQFLDEEK FKETVHKLEQ ESGFFFNMKY FEDEVHNGNW DEVEKYLSGF TKVDDNRYSM KIFFEIRKQK YLEALDKHDR PKAVDILVKD 0101: LKVFSTFNEE LFKEITQLLT LENFRENEQL SKYGDTKSAR AIMLVELKKL IEANPLFRDK LQFPTLRNSR LRTLINQSLN WQHQLCKNPR PNPDIKTLFV 0201: DHSCGPPNGA RAPSPVNNPL LGGIPKAGGF PPLGAHGPFQ PTASPVPTPL AGWMSSPSSV PHPAVSAGAI ALGGPSIPAA LKHPRTPPTN ASLDYPSADS 0301: EHVSKRTRPM GISDEVNLGV NMLPMSFSGQ AHGHSPAFKA PDDLPKTVAR TLSQGSSPMS MDFHPIKQTL LLVGTNVGDI GLWEVGSRER LVQKTFKVWD 0401: LSKCSMPLQA ALVKEPVVSV NRVIWSPDGS LFGVAYSRHI VQLYSYHGGE DMRQHLEIDA HVGGVNDISF STPNKQLCVI TCGDDKTIKV WDAATGVKRH 0501: TFEGHEAPVY SVCPHYKENI QFIFSTALDG KIKAWLYDNM GSRVDYDAPG RWCTTMAYSA DGTRLFSCGT SKDGESFIVE WNESEGAVKR TYQGFHKRSL 0601: GVVQFDTTKN RYLAAGDDFS IKFWDMDAVQ LLTAIDGDGG LQASPRIRFN KEGSLLAVSG NENVIKIMAN SDGLRLLHTF ENISSESSKP AINSIAAAAA 0701: AAATSAGHAD RSANVVSIQG MNGDSRNMVD VKPVITEESN DKSKIWKLTE VSEPSQCRSL RLPENLRVAK ISRLIFTNSG NAILALASNA IHLLWKWQRN 0801: ERNATGKATA SLPPQQWQPA SGILMTNDVA ETNPEEAVPC FALSKNDSYV MSASGGKISL FNMMTFKTMA TFMPPPPAAT FLAFHPQDNN IIAIGMDDST 0901: IQIYNVRVDE VKSKLKGHSK RITGLAFSNV LNVLVSSGAD AQLCVWNTDG WEKQRSKVLP LPQGRPNSAP SDTRVQFHQD QAHFLVVHET QLAIYETTKL 1001: ECMKQWAVRE SLAPITHATF SCDSQLVYAS FMDATVCVFS SANLRLRCRV NPSAYLPASL SNSNVHPLVI AAHPQEPNMF AVGLSDGGVH IFEPLESEGK 1101: WGVAPPAENG SASGAPTAPS VGASASDQPQ R |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)