suba logo
AT1G10670.3
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : ATP-citrate lyase A-1
Curator
Summary (TAIR10)
One of the three genes encoding subunit A of the trimeric protein ATP Citrate Lyase. Antisense ACLA-1 plants cause a reduction in cytosolic acetyl-CoA metabolism and have upregulation of stress-related genes and down-regulation of primary metabolism and growth genes, suggesting the mutation restricts normal growth and developmental processes and puts the plant into a state of stress.
Computational
Description (TAIR10)
ATP-citrate lyase A-1 (ACLA-1); CONTAINS InterPro DOMAIN/s: ATP-grasp fold, subdomain 2 (InterPro:IPR013816), ATP-grasp fold, succinyl-CoA synthetase-type (InterPro:IPR013650), Succinyl-CoA synthetase-like (InterPro:IPR016102); BEST Arabidopsis thaliana protein match is: ATP-citrate lyase A-2 (TAIR:AT1G60810.1).
Protein Annotations
eggNOG:COG0045eggNOG:KOG1254EMBL:CP002684EnsemblPlants:AT1G10670
EnsemblPlants:AT1G10670.3entrez:837610ExpressionAtlas:F4I5V8Gene3D:3.30.470.20
Gene3D:3.40.50.261GeneID:837610GO:GO:0005524GO:GO:0016829
Gramene:AT1G10670.3hmmpanther:PTHR23118InterPro:IPR013650InterPro:IPR013816
InterPro:IPR016102InterPro:IPR032263KEGG:00020+2.3.3.8KEGG:00020+6.2.1.5
KEGG:00640+6.2.1.5KEGG:00660+6.2.1.5KEGG:00720+2.3.3.8KEGG:00720+6.2.1.5
KEGG:ath:AT1G10670KO:K01648OMA:HHVINETPaxDb:F4I5V8
Pfam:PF08442Pfam:PF16114PRIDE:F4I5V8ProteinModelPortal:F4I5V8
Proteomes:UP000006548RefSeq:NP_001184953.1SMR:F4I5V8STRING:3702.AT1G10670.3
SUPFAM:SSF52210SUPFAM:SSF56059TAIR:AT1G10670tair10-symbols:ACLA-1
UniGene:At.21738unipathway:UPA00223UniProt:F4I5V8
Coordinates (TAIR10) chr1:+:3535787..3538098
Molecular Weight (calculated) 49052.10 Da
IEP (calculated) 5.27
GRAVY (calculated) -0.09
Length 443 amino acids
Sequence (TAIR10)
(BLAST)
001: MARKKIREYD SKRLVKEHFK RLSGKELPIR SVQADDVFWL HSCFGFSDIR HHVINETTDL NELVEKEPWL SSEKLVVKPD MLFGKRGKSG LVALKLDFAD
101: VATFVKERLG KEVEMSGCKG PITTFIVEPF VPHNEEYYLN VVSDRLGCSI SFSECGGIEI EENWDKVKTI FLPTGASLTP EICAPLVATL PLEIKAEIEE
201: FIKVIFTLFQ DLDFTFLEMN PFTLVDGSPY PLDMRGELDD TAAFKNFKKW GDIEFPLPFG RVMSPTESFI HGLDEKTSAS LKFTVLNPKG RIWTMVAGGG
301: ASVIYADTVG DLGYASELGN YAEYSGAPKE DEVLQYARVV IDCATANPDG KSRALVIGGG IANFTDVAAT FNGIIRALKE KEAKLKAARM HIFVRRGGPN
401: YQKGLAKMRA LGDDIGVPIE VYGPEATMTG ICKEAIQYIT AAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)