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AT1G10670.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : ATP-citrate lyase A-1
Curator
Summary (TAIR10)
One of the three genes encoding subunit A of the trimeric protein ATP Citrate Lyase. Antisense ACLA-1 plants cause a reduction in cytosolic acetyl-CoA metabolism and have upregulation of stress-related genes and down-regulation of primary metabolism and growth genes, suggesting the mutation restricts normal growth and developmental processes and puts the plant into a state of stress.
Computational
Description (TAIR10)
ATP-citrate lyase A-1 (ACLA-1); CONTAINS InterPro DOMAIN/s: ATP-grasp fold, subdomain 2 (InterPro:IPR013816), ATP-grasp fold, succinyl-CoA synthetase-type (InterPro:IPR013650), Succinyl-CoA synthetase-like (InterPro:IPR016102); BEST Arabidopsis thaliana protein match is: ATP-citrate lyase A-2 (TAIR:AT1G60810.1); Has 5465 Blast hits to 5464 proteins in 1555 species: Archae - 120; Bacteria - 3046; Metazoa - 362; Fungi - 200; Plants - 107; Viruses - 0; Other Eukaryotes - 1630 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1012-MONOMERBioCyc:ARA:GQT-1013-MONOMERBioCyc:ARA:GQT-220-MONOMERBioCyc:MetaCyc:AT1G10670-MONOMER
BioGrid:22850EC:2.3.3.8eggNOG:COG0045eggNOG:KOG1254
EMBL:AC009398EMBL:AK222079EMBL:AK230271EMBL:AY056213
EMBL:AY056593EMBL:AY087536EMBL:AY094479EMBL:AY113979
EMBL:CP002684EnsemblPlants:AT1G10670EnsemblPlants:AT1G10670.1EnsemblPlants:AT1G10670.2
EnsemblPlants:AT1G10670.4entrez:837610ExpressionAtlas:Q9SGY2Gene3D:3.30.470.20
Gene3D:3.40.50.261GeneID:837610Genevisible:Q9SGY2GO:GO:0003878
GO:GO:0005524GO:GO:0005829GO:GO:0006629hmmpanther:PTHR23118
HOGENOM:HOG000151490InParanoid:Q9SGY2InterPro:IPR013650InterPro:IPR013816
InterPro:IPR016102InterPro:IPR032263iPTMnet:Q9SGY2KEGG:00020+2.3.3.8
KEGG:00020+6.2.1.5KEGG:00640+6.2.1.5KEGG:00660+6.2.1.5KEGG:00720+2.3.3.8
KEGG:00720+6.2.1.5PaxDb:Q9SGY2Pfam:PF08442Pfam:PF16114
Pfam:Q9SGY2PhylomeDB:Q9SGY2PRIDE:Q9SGY2PRO:PR:Q9SGY2
ProteinModelPortal:Q9SGY2Proteomes:UP000006548RefSeq:NP_001184954.1RefSeq:NP_172537.1
RefSeq:NP_849634.1SMR:Q9SGY2STRING:3702.AT1G10670.3SUPFAM:SSF52210
SUPFAM:SSF56059TAIR:AT1G10670tair10-symbols:ACLA-1UniGene:At.21738
unipathway:UPA00223UniProt:Q9SGY2
Coordinates (TAIR10) chr1:+:3535787..3538098
Molecular Weight (calculated) 46681.40 Da
IEP (calculated) 5.16
GRAVY (calculated) -0.10
Length 423 amino acids
Sequence (TAIR10)
(BLAST)
001: MARKKIREYD SKRLVKEHFK RLSGKELPIR SVQINETTDL NELVEKEPWL SSEKLVVKPD MLFGKRGKSG LVALKLDFAD VATFVKERLG KEVEMSGCKG
101: PITTFIVEPF VPHNEEYYLN VVSDRLGCSI SFSECGGIEI EENWDKVKTI FLPTGASLTP EICAPLVATL PLEIKAEIEE FIKVIFTLFQ DLDFTFLEMN
201: PFTLVDGSPY PLDMRGELDD TAAFKNFKKW GDIEFPLPFG RVMSPTESFI HGLDEKTSAS LKFTVLNPKG RIWTMVAGGG ASVIYADTVG DLGYASELGN
301: YAEYSGAPKE DEVLQYARVV IDCATANPDG KSRALVIGGG IANFTDVAAT FNGIIRALKE KEAKLKAARM HIFVRRGGPN YQKGLAKMRA LGDDIGVPIE
401: VYGPEATMTG ICKEAIQYIT AAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)