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AT1G06220.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.989
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27177187 (2016): nucleus
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24832081 (2014): nucleus
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22550958 (2012): plastid
  • PMID:21433285 (2011): plasma membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Ribosomal protein S5/Elongation factor G/III/V family protein
Curator
Summary (TAIR10)
Encodes a protein with similarity to splicing factor Snu114. Snu114 is thought to be involved in activation of the splicosome. Loss of GFA1 function results in reduced female fertility. Approximately 50% of ovules abort due to defects in the female gametophyte. In mutant gametophytes antipodal cells express egg cell markers suggesting a defect in specification of cell fate.GFA1 is also required to restrict the expression of LIS.
Computational
Description (TAIR10)
MATERNAL EFFECT EMBRYO ARREST 5 (MEE5); FUNCTIONS IN: translation factor activity, nucleic acid binding, GTP binding, translation elongation factor activity, GTPase activity; INVOLVED IN: regulation of embryo sac egg cell differentiation, embryo development ending in seed dormancy; LOCATED IN: nuclear speck, cell wall, plasma membrane; EXPRESSED IN: whole plant, cultured cell; CONTAINS InterPro DOMAIN/s: Protein synthesis factor, GTP-binding (InterPro:IPR000795), Translation elongation factor EFG/EF2, domain IV (InterPro:IPR005517), Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFG/EF2, C-terminal (InterPro:IPR000640), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), Elongation factor G/III/V (InterPro:IPR009022), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Ribosomal protein S5/Elongation factor G/III/V family protein (TAIR:AT5G25230.1); Has 61019 Blast hits to 57504 proteins in 4658 species: Archae - 1314; Bacteria - 38464; Metazoa - 2393; Fungi - 1714; Plants - 1333; Viruses - 1; Other Eukaryotes - 15800 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0480eggNOG:KOG0468EMBL:AC025290EMBL:AK226591
EMBL:CP002684EnsemblPlants:AT1G06220EnsemblPlants:AT1G06220.1EnsemblPlants:AT1G06220.2
entrez:837131Gene3D:3.30.230.10Gene3D:3.30.70.240Gene3D:3.40.50.300
GeneID:837131GO:GO:0003924GO:GO:0005525GO:GO:0005618
GO:GO:0005886GO:GO:0009793GO:GO:0016607GO:GO:0045694
Gramene:AT1G06220.1Gramene:AT1G06220.2hmmpanther:PTHR23115hmmpanther:PTHR23115:SF5
HOGENOM:HOG000231589IntAct:Q9LNC5InterPro:IPR000640InterPro:IPR000795
InterPro:IPR004161InterPro:IPR005225InterPro:IPR005517InterPro:IPR009000
InterPro:IPR009022InterPro:IPR014721InterPro:IPR020568InterPro:IPR027417
InterPro:IPR031950KEGG:ath:AT1G06220KO:K12852OMA:PTDTSIK
Pfam:PF00009Pfam:PF00679Pfam:PF03144Pfam:PF03764
Pfam:PF16004Pfscan:PS51722PhylomeDB:Q9LNC5PIR:H86197
PRINTS:PR00315PROSITE:PS51722Proteomes:UP000006548Reactome:R-ATH-72163
Reactome:R-ATH-72165RefSeq:NP_172112.1RefSeq:NP_849600.1SMART:SM00838
SMART:SM00889SMR:Q9LNC5STRING:3702.AT1G06220.1SUPFAM:SSF50447
SUPFAM:SSF52540SUPFAM:SSF54211SUPFAM:SSF54980TAIR:AT1G06220
tair10-symbols:CLOtair10-symbols:GFA1tair10-symbols:MEE5TIGRfam:TIGR00231
TIGRFAMs:TIGR00231UniGene:At.15476UniGene:At.67274UniProt:Q9LNC5
Coordinates (TAIR10) chr1:+:1900524..1904583
Molecular Weight (calculated) 110448.00 Da
IEP (calculated) 4.82
GRAVY (calculated) -0.26
Length 987 amino acids
Sequence (TAIR10)
(BLAST)
001: MESSLYDEFG NYVGPEIESD RDSDDEVEDE DLQDKHLEEN GSDGEQGPGG SNGWITTIND VEMENQIVLP EDKKYYPTAE EVYGEDVETL VMDEDEQPLE
101: QPIIKPVRDI RFEVGVKDQA TYVSTQFLIG LMSNPALVRN VALVGHLQHG KTVFMDMLVE QTHHMSTFNA KNEKHMKYTD TRVDEQERNI SIKAVPMSLV
201: LEDSRSKSYL CNIMDTPGHV NFSDEMTASL RLADGAVLIV DAAEGVMVNT ERAIRHAIQD HLPIVVVINK VDRLITELKL PPRDAYYKLR HTIEVINNHI
301: SAASTTAGDL PLIDPAAGNV CFASGTAGWS FTLQSFAKMY AKLHGVAMDV DKFASRLWGD VYYHSDTRVF KRSPPVGGGE RAFVQFILEP LYKIYSQVIG
401: EHKKSVETTL AELGVTLSNS AYKLNVRPLL RLACSSVFGS ASGFTDMLVK HIPSPREAAA RKVDHSYTGT KDSPIYESMV ECDPSGPLMV NVTKLYPKSD
501: TSVFDVFGRV YSGRLQTGQS VRVLGEGYSP EDEEDMTIKE VTKLWIYQAR YRIPVSSAPP GSWVLIEGVD ASIMKTATLC NASYDEDVYI FRALQFNTLP
601: VVKTATEPLN PSELPKMVEG LRKISKSYPL AITKVEESGE HTILGTGELY LDSIMKDLRE LYSEVEVKVA DPVVSFCETV VESSSMKCFA ETPNKKNKIT
701: MIAEPLDRGL AEDIENGVVS IDWNRKQLGD FFRTKYDWDL LAARSIWAFG PDKQGPNILL DDTLPTEVDR NLMMAVKDSI VQGFQWGARE GPLCDEPIRN
801: VKFKIVDARI APEPLHRGSG QMIPTARRVA YSAFLMATPR LMEPVYYVEI QTPIDCVTAI YTVLSRRRGH VTSDVPQPGT PAYIVKAFLP VIESFGFETD
901: LRYHTQGQAF CLSVFDHWAI VPGDPLDKAI QLRPLEPAPI QHLAREFMVK TRRRKGMSED VSGNKFFDEA MMVELAQQTG DLHLQMI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)