AT1G01040.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : dicer-like 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
dicer-like 1 (DCL1); CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), Double-stranded RNA-binding-like (InterPro:IPR014720), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Dicer double-stranded RNA-binding fold (InterPro:IPR005034), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: dicer-like 3 (TAIR:AT3G43920.1). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:23519..31079 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 213684.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.16 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.41 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1910 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MVMEDEPREA TIKPSYWLDA CEDISCDLID DLVSEFDPSS VAVNESTDEN GVINDFFGGI DHILDSIKNG GGLPNNGVSD TNSQINEVTV TPQVIAKETV 0101: KENGLQKNGG KRDEFSKEEG DKDRKRARVC SYQSERSNLS GRGHVNNSRE GDRFMNRKRT RNWDEAGNNK KKRECNNYRR DGRDREVRGY WERDKVGSNE 0201: LVYRSGTWEA DHERDVKKVS GGNRECDVKA EENKSKPEER KEKVVEEQAR RYQLDVLEQA KAKNTIAFLE TGAGKTLIAI LLIKSVHKDL MSQNRKMLSV 0301: FLVPKVPLVY QQAEVIRNQT CFQVGHYCGE MGQDFWDSRR WQREFESKQV LVMTAQILLN ILRHSIIRME TIDLLILDEC HHAVKKHPYS LVMSEFYHTT 0401: PKDKRPAIFG MTASPVNLKG VSSQVDCAIK IRNLETKLDS TVCTIKDRKE LEKHVPMPSE IVVEYDKAAT MWSLHETIKQ MIAAVEEAAQ ASSRKSKWQF 0501: MGARDAGAKD ELRQVYGVSE RTESDGAANL IHKLRAINYT LAELGQWCAY KVGQSFLSAL QSDERVNFQV DVKFQESYLS EVVSLLQCEL LEGAAAEKVA 0601: AEVGKPENGN AHDEMEEGEL PDDPVVSGGE HVDEVIGAAV ADGKVTPKVQ SLIKLLLKYQ HTADFRAIVF VERVVAALVL PKVFAELPSL SFIRCASMIG 0701: HNNSQEMKSS QMQDTISKFR DGHVTLLVAT SVAEEGLDIR QCNVVMRFDL AKTVLAYIQS RGRARKPGSD YILMVERGNV SHAAFLRNAR NSEETLRKEA 0801: IERTDLSHLK DTSRLISIDA VPGTVYKVEA TGAMVSLNSA VGLVHFYCSQ LPGDRYAILR PEFSMEKHEK PGGHTEYSCR LQLPCNAPFE ILEGPVCSSM 0901: RLAQQAVCLA ACKKLHEMGA FTDMLLPDKG SGQDAEKADQ DDEGEPVPGT ARHREFYPEG VADVLKGEWV SSGKEVCESS KLFHLYMYNV RCVDFGSSKD 1001: PFLSEVSEFA ILFGNELDAE VVLSMSMDLY VARAMITKAS LAFKGSLDIT ENQLSSLKKF HVRLMSIVLD VDVEPSTTPW DPAKAYLFVP VTDNTSMEPI 1101: KGINWELVEK ITKTTAWDNP LQRARPDVYL GTNERTLGGD RREYGFGKLR HNIVFGQKSH PTYGIRGAVA SFDVVRASGL LPVRDAFEKE VEEDLSKGKL 1201: MMADGCMVAE DLIGKIVTAA HSGKRFYVDS ICYDMSAETS FPRKEGYLGP LEYNTYADYY KQKYGVDLNC KQQPLIKGRG VSYCKNLLSP RFEQSGESET 1301: VLDKTYYVFL PPELCVVHPL SGSLIRGAQR LPSIMRRVES MLLAVQLKNL ISYPIPTSKI LEALTAASCQ ETFCYERAEL LGDAYLKWVV SRFLFLKYPQ 1401: KHEGQLTRMR QQMVSNMVLY QFALVKGLQS YIQADRFAPS RWSAPGVPPV FDEDTKDGGS SFFDEEQKPV SEENSDVFED GEMEDGELEG DLSSYRVLSS 1501: KTLADVVEAL IGVYYVEGGK IAANHLMKWI GIHVEDDPDE VDGTLKNVNV PESVLKSIDF VGLERALKYE FKEKGLLVEA ITHASRPSSG VSCYQRLEFV 1601: GDAVLDHLIT RHLFFTYTSL PPGRLTDLRA AAVNNENFAR VAVKHKLHLY LRHGSSALEK QIREFVKEVQ TESSKPGFNS FGLGDCKAPK VLGDIVESIA 1701: GAIFLDSGKD TTAAWKVFQP LLQPMVTPET LPMHPVRELQ ERCQQQAEGL EYKASRSGNT ATVEVFIDGV QVGVAQNPQK KMAQKLAARN ALAALKEKEI 1801: AESKEKHINN GNAGEDQGEN ENGNKKNGHQ PFTRQTLNDI CLRKNWPMPS YRCVKEGGPA HAKRFTFGVR VNTSDRGWTD ECIGEPMPSV KKAKDSAAVL 1901: LLELLNKTFS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)